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“突破出血”:合并抗凝治疗的气肿性大疱自发性出血一例报告

"Breaking the Bleed" Spontaneous Hemorrhage in an Emphysematous Bulla Complicated by Anticoagulation: A Case Report.

作者信息

Shaikh Fahad H, Zerilli Nicholas A, Jamil Taimoor, Ishtiaq Daniyal, Avasthi Deepti

机构信息

Internal Medicine, Mercy Health St. Vincent Medical Center, Toledo, USA.

Internal Medicine, Mercy Health, Toledo, USA.

出版信息

Cureus. 2024 Dec 29;16(12):e76574. doi: 10.7759/cureus.76574. eCollection 2024 Dec.

Abstract

We present a case of spontaneous hemorrhage in an emphysematous bulla, complicated by anticoagulation. Bullous emphysema is a well-recognized complication of chronic obstructive pulmonary disease (COPD), and a rare manifestation is hemorrhage into preexisting pulmonary bullae. A 69-year-old male patient presented to the emergency department with hemoptysis, shortness of breath, and productive cough. He had a history of COPD, coronary artery disease, congestive heart failure, and paroxysmal atrial fibrillation, managed with aspirin and rivaroxaban. Chest imaging revealed fluid-filled bulla in the left lower lobe, suggesting spontaneous hemorrhage into an emphysematous bulla. Bronchoscopy confirmed active bleeding, and the patient was managed with medical therapy and video-assisted thoracoscopic surgery with bullectomy. The patient recovered well post-operatively, with no further episodes of bleeding. Long-term follow-up showed improved respiratory function and the successful placement of a left atrial appendage closure device to manage atrial fibrillation to obviate the need for long-term anticoagulation. In this report, we will discuss prior cases of this condition and its management. This case not only sheds light on the rare and complex clinical scenario of a spontaneous bleed in a pre-existing emphysematous bulla but also underscores the successful use of surgical resection in a context where surgical management is not often used. Our patient's positive outcome and recovery over seven months, as evidenced by close longitudinal follow-up, provides valuable insights into the potential benefits of surgical intervention in select cases.

摘要

我们报告一例肺气肿性肺大疱自发性出血病例,该病例合并抗凝治疗。肺大疱性肺气肿是慢性阻塞性肺疾病(COPD)的一种公认并发症,而肺大疱内出血是一种罕见表现。一名69岁男性患者因咯血、呼吸急促和咳痰就诊于急诊科。他有慢性阻塞性肺疾病、冠状动脉疾病、充血性心力衰竭和阵发性心房颤动病史,接受阿司匹林和利伐沙班治疗。胸部影像学检查显示左肺下叶有液性肺大疱,提示肺气肿性肺大疱自发性出血。支气管镜检查证实有活动性出血,患者接受了药物治疗和胸腔镜辅助下肺大疱切除术。患者术后恢复良好,未再出现出血情况。长期随访显示呼吸功能改善,成功植入左心耳封堵装置以治疗心房颤动,从而避免长期抗凝治疗。在本报告中,我们将讨论该病症的既往病例及其治疗方法。该病例不仅揭示了既往存在的肺气肿性肺大疱自发性出血这一罕见且复杂的临床情况,还强调了在通常不采用手术治疗的情况下手术切除的成功应用。通过密切的纵向随访证明,我们的患者在七个月内取得了积极的治疗效果并康复,这为特定病例中手术干预的潜在益处提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b23/11774445/c03cd8c7085d/cureus-0016-00000076574-i01.jpg

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