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基于日常生活基本活动功能依赖的死亡风险评估对巴氏指数分类进行修订的提议。

Proposal for a revised Barthel index classification based on mortality risk assessment in functional dependence for basic activities of daily living.

作者信息

Martín Moreno Vicente, Martínez Sanz María Inmaculada, Martín Fernández Amanda, Guerra Maroto Sara, Sevillano Fuentes Eva, Pérez Rico Elena, Sánchez González Irene, Fernández Gallardo Miriam, Herranz Hernando Julia, Benítez Calderón María Palma, Calderón Jiménez Laura, Sánchez Rodríguez Elena, Recuero Vázquez Miguel, Alonso Samperiz Helena, León Saiz Irene, Marcos Guerra Juana

机构信息

Orcasitas Health Care Center, Madrid, Spain.

i+12 Research Institute, Doce de Octubre Hospital, Madrid, Spain.

出版信息

Front Public Health. 2025 Jan 14;12:1478897. doi: 10.3389/fpubh.2024.1478897. eCollection 2024.

DOI:10.3389/fpubh.2024.1478897
PMID:39877909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11772177/
Abstract

INTRODUCTION

Functional dependence on the performance of basic activities of daily living (ADLs) is associated with increased mortality. In this study, the Barthel index and its activities discriminate long-term mortality risk, and whether changes in this index are necessary to adapt it to detect mortality risk is examined.

METHODS

Longitudinal study, carried out at the Orcasitas Health Center, Madrid (Spain), on the functional dependent population (Barthel ≤ 60). It included 127 people, with a mean age of 86 years (78.7% women and 21.3% men). Functional capacity was assessed using the Barthel index, and this index and each item it contains were analyzed as a test in relation to survival at three years, using tools that evaluate precision, discrimination, and calibration. The date of death was obtained from the health system.

RESULTS

Greater dependency to perform chair-to-bed transfers was associated with an increased mortality risk (HR 2.957; CI 1.678-5.211). Also, individuals with severe (HR 0.492; CI 0.290-0.865) and moderate (HR 0.574; CI 0.355-0.927) ADL dependence had a reduced mortality risk when more independent in chair-to-bed transfers. Among people with moderate ADL dependence, this percentage was 48%. Using dependence-independence for chair-to-bed transfer as a screening test for mortality, the test showed high sensitivity (0.91) and specificity (0.83), a positive likelihood ratio of 5.45, and a negative likelihood ratio of 0.11. The area under the ROC curve was 0.814 (CI 0.658-0.970;  = 0.001), with a  = 0.235;  = 0.889, according to the Hosmer-Lemeshow test. The concordance C index was 0.814. According to Nagelkerke's R, the model explained 53.1% of the variance in survival. As a screening test, "chair-to-bed transfer" was superior to the Barthel index.

CONCLUSION

ADL dependence for chair-to-bed transfers is an independent risk factor for mortality for any level of dependency. Therefore, a new classification of the Barthel index is proposed, in which "being dependent or requiring great assistance to perform chair-to-bed transfers" is considered severe dependence, even when the total score obtained via the Barthel Index is ≥40. We propose its use as a screening test in parallel to the Barthel index. The study suggests that the Barthel Index may have limitations in adequately discriminating mortality risk.

摘要

引言

对日常生活基本活动(ADL)表现的功能依赖与死亡率增加相关。在本研究中,巴氏指数及其各项活动可区分长期死亡风险,并探讨该指数的变化是否有必要进行调整以检测死亡风险。

方法

在西班牙马德里的奥卡西塔斯健康中心对功能依赖人群(巴氏指数≤60)进行纵向研究。研究纳入了127人,平均年龄86岁(女性占78.7%,男性占21.3%)。使用巴氏指数评估功能能力,并使用评估准确性、区分度和校准度的工具,将该指数及其包含的每个项目作为一项关于三年生存率的测试进行分析。死亡日期从卫生系统获取。

结果

从椅子坐到床上转移的依赖性越强,死亡风险越高(风险比2.957;置信区间1.678 - 5.211)。此外,在从椅子坐到床上转移方面更独立时,重度(风险比0.492;置信区间0.290 - 0.865)和中度(风险比0.574;置信区间0.355 - 0.927)ADL依赖个体的死亡风险降低。在中度ADL依赖人群中,这一比例为48%。将从椅子坐到床上转移的依赖 - 独立情况用作死亡筛查测试时,该测试显示出高敏感性(0.91)和特异性(0.83),阳性似然比为5.45,阴性似然比为0.11。根据Hosmer - Lemeshow检验,ROC曲线下面积为0.814(置信区间0.658 - 0.970;P = 0.001),其中χ² = 0.235;P = 0.889。一致性C指数为0.814。根据Nagelkerke's R,该模型解释了生存率方差的53.1%。作为筛查测试,“从椅子坐到床上转移”优于巴氏指数。

结论

对于任何依赖程度,从椅子坐到床上转移的ADL依赖都是死亡的独立危险因素。因此,提出了巴氏指数的新分类,即即使通过巴氏指数获得的总分≥40,“在从椅子坐到床上转移时依赖或需要极大帮助”也被视为重度依赖。我们建议将其与巴氏指数并行用作筛查测试。该研究表明巴氏指数在充分区分死亡风险方面可能存在局限性。

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