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大鼠四氧嘧啶糖尿病早期从绒毛 - 隐窝轴分离的肠上皮细胞刷状缘酶活性的变化。

Changes in brush-border enzyme activities of intestinal epithelial cells isolated from the villus-crypt axis during the early phase of alloxan diabetes in rats.

作者信息

Nakabou Y, Ikeuchi K, Minami H, Hagihira H

出版信息

Experientia. 1985 Apr 15;41(4):482-4. doi: 10.1007/BF01966159.

DOI:10.1007/BF01966159
PMID:3987870
Abstract

The sucrase activity in enterocytes isolated from the villus crypt axis was found to increase in all regions of the villus from day 2 after induction of diabetes, and the increase continued until day 4. In contrast, alkaline phosphatase activity increased mainly in the apical one-third of the villus-crypt column, and the increase occurred abruptly on day 4 with increase in food intake.

摘要

从绒毛隐窝轴分离的肠上皮细胞中的蔗糖酶活性在糖尿病诱导后第2天起在绒毛的所有区域均增加，并持续增加至第4天。相比之下，碱性磷酸酶活性主要在绒毛-隐窝柱的顶端三分之一处增加，且在第4天随着食物摄入量的增加而突然增加。

相似文献

1
Changes in brush-border enzyme activities of intestinal epithelial cells isolated from the villus-crypt axis during the early phase of alloxan diabetes in rats.大鼠四氧嘧啶糖尿病早期从绒毛 - 隐窝轴分离的肠上皮细胞刷状缘酶活性的变化。
Experientia. 1985 Apr 15;41(4):482-4. doi: 10.1007/BF01966159.
2
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Indian J Biochem Biophys. 1993 Jun;30(3):177-80.
3
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Can J Physiol Pharmacol. 1987 Jun;65(6):1213-9. doi: 10.1139/y87-191.

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本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Amino acid balance and imbalance. I. Dietary level of protein and amino acid imbalance.
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Immediate and localized response of intestinal mucosal enzyme activities in streptozotocin-diabetic mice.链脲佐菌素诱导的糖尿病小鼠肠道黏膜酶活性的即时局部反应
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Assay of intestinal disaccharidases.肠道双糖酶测定
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Jejunal sucrase activity in diabetic rats.糖尿病大鼠空肠蔗糖酶活性
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7
Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation.肠上皮细胞表面膜糖蛋白的合成。I. 细胞分化的一个指标。
J Biol Chem. 1973 Apr 10;248(7):2536-41.
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Daily rhythmic changes in brush border enzymes of the small intestine and kidney in rat.
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Rat intestinal microvillus membranes. Purification and biochemical characterization.大鼠肠道微绒毛膜。纯化及生化特性分析。
Biochem J. 1968 Jan;106(2):381-90. doi: 10.1042/bj1060381.
10
Increase of intestinal brush border hydrolases in mucosa of streptozotocin-diabetic rats.链脲佐菌素诱导的糖尿病大鼠肠黏膜刷状缘水解酶活性增加。
Diabetologia. 1972 Dec;8(6):412-4. doi: 10.1007/BF01212169.