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阿拉伯联合酋长国EQ-5D-5L的价值集

A Value Set for EQ-5D-5L in the United Arab Emirates.

作者信息

Al Sayah Fatima, Roudijk Bram, El Sadig Mohamed, Al Mannaei Asma, Farghaly Mohamad N, Dallal Sara, Kaddoura Rima, Metni Mirna, Elbarazi Iffat, Kharroubi Samer A

机构信息

Center for Clinical, Health Economics and Outcomes Research (CCHO), Dubai, United Arab Emirates.

EuroQol Research Foundation, Rotterdam, The Netherlands.

出版信息

Value Health. 2025 Apr;28(4):611-621. doi: 10.1016/j.jval.2025.01.003. Epub 2025 Jan 27.

Abstract

OBJECTIVES

This study aimed to develop a value set for the EQ-5D-5L based on preferences of the general adult population of the United Arab Emirates (UAE).

METHODS

The study followed the EuroQol EQ-5D-5L valuation protocol and involved conducting interviewer-administered face-to-face or online interviews in Arabic or English, using the EuroQol Valuation Technology with a sample of 1005 adults representing the UAE general population. Sample recruitment involved a 2-stage quota sampling strategy across the 7 emirates of the UAE, ensuring representation of nationals and expatriates. Various models using composite time trade-off data only, discrete choice experiment data only, and hybrid using both composite time trade-off and discrete choice experiment data were examined, along with various sensitivity analyses to examine the robustness of the models.

RESULTS

The average age of respondents was 39 years (SD 10.8), 44.5% were female, and 11% were UAE nationals. The best-performing model to generate the value set for the EQ-5D-5L was the hybrid tobit model censored at -1.0, corrected for heteroskedasticity. Values ranged from -0.654 for the worst health state (55555) to 1 for full health (11111) and 0.962 for 11211, with 15.3% of predicted values worse than dead. Mobility problems had the largest impact on health state preference values relative to other dimensions.

CONCLUSION

This value set will facilitate the application and use of the EQ-5D-5L instrument in the UAE population in generating local evidence on the cost-effectiveness of healthcare interventions, as well as to enhance other applications of EQ-5D in population health assessment and health systems.

摘要

目的

本研究旨在根据阿拉伯联合酋长国(阿联酋)普通成年人群的偏好,制定EQ-5D-5L的价值集。

方法

该研究遵循欧洲生活质量五维度五水平(EQ-5D-5L)估值方案,采用欧洲生活质量估值技术,以1005名代表阿联酋普通人群的成年人作为样本,通过面对面或在线访谈的方式,由访谈员用阿拉伯语或英语进行调查。样本招募采用两阶段配额抽样策略,覆盖阿联酋的7个酋长国,以确保本国人和外籍人士都有代表性。研究考察了仅使用复合时间权衡数据、仅使用离散选择实验数据以及同时使用复合时间权衡和离散选择实验数据的各种模型,并进行了各种敏感性分析以检验模型的稳健性。

结果

受访者的平均年龄为39岁(标准差10.8),44.5%为女性,11%为阿联酋国民。生成EQ-5D-5L价值集的最佳模型是经异方差校正、截尾值为-1.0的混合托比特模型。价值范围从最差健康状态(55555)的-0.654到完全健康(11111)的1以及11211的0.962,有15.3%的预测值比死亡还差。相对于其他维度,行动能力问题对健康状态偏好值的影响最大。

结论

该价值集将有助于在阿联酋人群中应用和使用EQ-5D-5L工具,以生成关于医疗保健干预措施成本效益的本地证据,并加强EQ-5D在人群健康评估和卫生系统中的其他应用。

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