Mehta Kanika, Randall Sean, Lee Crystal Man Ying, Thomas Elizabeth, Chakera Aron, Chai Kevin, Estai Mohamed, Frith Madison, Hendrie Delia, Boyd James, Robinson Suzanne
Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
Deakin Health Economics, Institute for Health Transformation, Deakin University, Melbourne, Victoria, Australia.
BMJ Open. 2025 Jan 28;15(1):e092320. doi: 10.1136/bmjopen-2024-092320.
To assess the prevalence and trends of chronic kidney disease (CKD) in Western Australia (WA) from 2010 to 2020 using linked pathology data.
A retrospective observational cohort study using linked de-identified data from WA pathology providers, hospital morbidity records and mortality records.
A Western Australian population-based study.
All individuals aged 18 years and older with at least one serum creatinine test.
CKD status as determined by estimated glomerular filtration rate and urine albumin-creatinine ratio.
Analysing data from 2 501 188 individuals, there was a significant increase in age-sex standardised CKD prevalence from 4.7% in 2010 to 6.0% in 2020, with annual average percentage change of 3.0% (95% CI: 2.3% to 3.7%). Prevalence of CKD stages 3 and above was 4.8% in 2020. Higher CKD prevalence was observed in regional and remote areas compared with major cities, and among individuals in the most socioeconomically disadvantaged quintiles. Sensitivity analysis indicated minor impacts from data exclusions and methodological choices.
CKD prevalence in WA has been steadily increasing, reflecting broader Australian trends. The study highlights significant disparities in CKD prevalence based on age, socioeconomic status and geographic remoteness.
利用关联病理数据评估2010年至2020年西澳大利亚州（WA）慢性肾脏病（CKD）的患病率及趋势。
一项回顾性观察队列研究，使用来自西澳大利亚州病理机构、医院发病率记录和死亡率记录的关联匿名数据。
一项基于西澳大利亚州人群的研究。
所有年龄在18岁及以上且至少进行过一次血清肌酐检测的个体。
根据估计肾小球滤过率和尿白蛋白肌酐比值确定的CKD状态。
分析2501188名个体的数据，年龄性别标准化的CKD患病率从2010年的4.7%显著增加到2020年的6.0%，年平均变化百分比为3.0%（95%CI：2.3%至3.7%）。2020年3期及以上CKD的患病率为4.8%。与主要城市相比，在地区和偏远地区以及社会经济最弱势五分之一人群中观察到更高的CKD患病率。敏感性分析表明数据排除和方法选择的影响较小。
西澳大利亚州CKD患病率一直在稳步上升，反映了澳大利亚更广泛的趋势。该研究突出了基于年龄、社会经济地位和地理偏远程度的CKD患病率的显著差异。
