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前路颈椎间盘切除并使用自锁独立椎间融合器融合术治疗80岁以上患者的颈椎间盘退变疾病

Anterior cervical discectomy and fusion with self-locking standalone cage for the treatment of cervical degenerative disc disease in patients over 80 years.

作者信息

Zhou Jian, Hu An'nan, Zhou Xiaogang, Dong Jian

机构信息

Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.

出版信息

J Orthop Traumatol. 2025 Jan 29;26(1):7. doi: 10.1186/s10195-025-00820-7.

Abstract

BACKGROUND

The need for anterior cervical discectomy and fusion (ACDF) for cervical degenerative disc disease (CDDD) will probably grow dramatically in the geriatric population. However, ACDF with self-locking standalone cages in patients over 80 years has not yet been investigated. This study aimed to assess the clinical and radiographic results in patients over 80 years treated by ACDF with self-locking standalone cages.

METHODS

Between January 2018 and December 2019, patients with CDDD treated with ACDF were retrospectively stratified into two groups: the older group (≥ 80 years) and the younger group (< 65 years). The data collected included the demographics, preoperative comorbidities, intraoperative parameters, length of hospital stay, complications, clinical scores, and radiological parameters.

RESULTS

A total of 123 patients were included in the study. The mean follow-up duration was 28.3 ± 2.4 months. The hospital stay was 5.3 ± 0.6 days and 3.8 ± 0.4 days, respectively, for the older and younger groups. Postoperative complication rate was found higher in the older group than that of the young group without significance. All the patient-reported outcome parameters had significant improvement at the final follow-up. The two groups had no significant differences in terms of the excellent and reasonable rates, fusion rate, and the C2-C7 Cobb angle.

CONCLUSIONS

Although a slightly higher incidence of complications, poorer recovery rate, and more extended hospital stay were found, without significant differences, satisfactory clinical and radiographic results were obtained in the older patients. The self-locking standalone cage is a safe and viable option for patients over 80 years who suffer from CDDD. Level of evidence Level IV.

摘要

背景

对于颈椎退行性椎间盘疾病(CDDD),老年人群对前路颈椎间盘切除融合术(ACDF)的需求可能会急剧增长。然而,80岁以上患者使用自锁独立椎间融合器进行ACDF的情况尚未得到研究。本研究旨在评估80岁以上患者使用自锁独立椎间融合器进行ACDF的临床和影像学结果。

方法

2018年1月至2019年12月期间,对接受ACDF治疗的CDDD患者进行回顾性分层,分为老年组(≥80岁)和年轻组(<65岁)。收集的数据包括人口统计学资料、术前合并症、术中参数、住院时间、并发症、临床评分和放射学参数。

结果

本研究共纳入123例患者。平均随访时间为28.3±2.4个月。老年组和年轻组的住院时间分别为5.3±0.6天和3.8±0.4天。老年组术后并发症发生率高于年轻组,但无统计学意义。所有患者报告的结局参数在末次随访时均有显著改善。两组在优良率、融合率和C2-C7 Cobb角方面无显著差异。

结论

虽然老年患者并发症发生率略高、恢复率较差且住院时间延长,但无显著差异,老年患者仍获得了满意的临床和影像学结果。自锁独立椎间融合器对于80岁以上患有CDDD的患者是一种安全可行的选择。证据级别:四级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2674/11780053/9e5b463bef79/10195_2025_820_Fig1_HTML.jpg

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