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年轻抗磷脂综合征患者慢性硬膜下血肿的脑膜中动脉栓塞术:一例报告

Middle meningeal artery embolization for chronic subdural hematoma in a young patient with antiphospholipid syndrome: A case report.

作者信息

Aagaard Kristoffer Ambeck, Einarsson Halldór Bjarki, Novrup Hans Værum Gram

机构信息

Department of Neurosurgery, Aalborg University Hospital, Aalborg, Denmark.

Department of Neuroradiology, Aalborg University Hospital, Aalborg, Denmark.

出版信息

SAGE Open Med Case Rep. 2025 Jan 28;13:2050313X251315032. doi: 10.1177/2050313X251315032. eCollection 2025.

Abstract

Chronic subdural hematoma is a common condition in neurosurgical practice. It is usually treated by burr-hole surgery. Patients with coagulopathies such as antiphospholipid syndrome, are at increased risk of complications, and careful consideration of the patient's specific risk of both bleeding and thromboembolic complications must guide medical management. We present the case of a 34-year-old who presented to the neurosurgical department with a chronic subdural hematoma. She had a medical history of triple-positive antiphospholipid syndrome, lupus, and mechanical aortic valve replacement due to Libman-Sacks endocarditis. It was considered of high risk to proceed with traditional burr-hole surgery, so instead embolization of the middle meningeal artery was performed. Postoperatively the patient gradually improved, and a scan at 6 months showed complete regression of the hematoma. She later presented with a contralateral subdural hematoma, which was also successfully treated with middle meningeal artery embolization. Unfortunately, she suffered from an intracerebral hemorrhage shortly afterward, which was treated conservatively by careful management of her anticoagulant therapy. She has now made a full recovery at 4 months follow-up.

摘要

慢性硬膜下血肿是神经外科临床常见病症。通常采用钻孔手术治疗。患有抗磷脂综合征等凝血功能障碍的患者,并发症风险增加,必须仔细考虑患者出血和血栓栓塞并发症的具体风险,以指导医疗管理。我们报告一例34岁患者,因慢性硬膜下血肿就诊于神经外科。她有抗磷脂综合征三联阳性、狼疮病史,因Libman-Sacks心内膜炎接受了机械主动脉瓣置换术。考虑到进行传统钻孔手术风险较高,因此改为进行脑膜中动脉栓塞术。术后患者逐渐好转,6个月时的扫描显示血肿完全消退。她后来又出现对侧硬膜下血肿,同样成功接受了脑膜中动脉栓塞术治疗。不幸的是,此后不久她发生了脑出血,通过谨慎管理抗凝治疗进行了保守治疗。在4个月的随访中,她现已完全康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10e3/11775960/8db58eff8d4e/10.1177_2050313X251315032-fig1.jpg

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