Ramachandran Rajarajeshwari, Grantham Tyler, Loeffler Jeffrey, Reddy Madhavi, Gaduputi Vinaya
Fresno Veterans Affairs Medical Center, CA, USA.
Staten Island University Hospital, NY, USA.
J Investig Med High Impact Case Rep. 2025 Jan-Dec;13:23247096251313729. doi: 10.1177/23247096251313729.
Oxyntic gland adenomas (OGAs) are benign gastric neoplasms composed of gland-forming epithelial cells with predominantly chief cell differentiation resembling oxyntic glands confined to the mucosa. If the tumor has submucosal invasion, it should be classified as gastric adenocarcinoma of fundic gland type. The OGAs can pose a diagnostic challenge, as they can resemble aggressive gastric neoplasms. There are no current guidelines on the management of OGA. Due to the relatively small size and low malignant potential, these lesions are typically managed endoscopically. In this case, we are reporting a 22-year-old woman who was diagnosed with OGA during evaluation of iron deficiency anemia and underwent successful endoscopic resection.
胃泌酸腺腺瘤（OGAs）是一种良性胃肿瘤，由形成腺体的上皮细胞组成，主要为壁细胞分化，类似于局限于黏膜层的胃泌酸腺。如果肿瘤侵犯黏膜下层，则应归类为胃底腺型腺癌。胃泌酸腺腺瘤可能带来诊断挑战，因为它们可能类似侵袭性胃肿瘤。目前尚无关于胃泌酸腺腺瘤管理的指南。由于这些病变相对较小且恶性潜能较低，通常通过内镜进行处理。在此病例中，我们报告一名22岁女性，她在缺铁性贫血评估期间被诊断为胃泌酸腺腺瘤，并成功接受了内镜切除。
