Lee Seon-Mi, Shin Daun, Seol Aeran, Lee Sanghoon, Cho Hyun-Woong, Min Kyung-Jin, Hong Jin-Hwa, Lee Jae-Kwan, Lee Nak-Woo, Song Jae-Yun, Choi Won Jun
Department of Obstetrics and Gynecology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Department of Obstetrics and Gynecology, Gyeongsang National University Hospital, College of Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Psychiatry Investig. 2025 Jan;22(1):57-65. doi: 10.30773/pi.2024.0222. Epub 2025 Jan 15.
Objective of this study is to evaluate the association between high risk of depression and metabolic diseases such as hypertension, diabetes, and dyslipidemia in Korean cervical cancer patients.
A total of 330 women with cervical cancer were included in this study, using data from the Korea National Health and Nutrition Examination Survey from 2010 to 2021. Participants were categorized into two groups-high risk of depression and non-depression-based on their answers to survey items related to depression. A multivariate logistic regression analysis was used to evaluate the influence of metabolic diseases on high risk of depression in patients with cervical cancer.
A total of 78 (23.64%) and 252 (76.36%) women were classified into the high risk of depression and non-depression groups, respectively. In multivariate logistic regression analysis adjusting for age, menopausal status, and smoking status, diabetes was associated with an odds ratio of 2.47 (95% confidence interval: 1.205, 5.071) for high risk of depression in cervical cancer patients. However, among the metabolic diseases, hypertension, and dyslipidemia were not associated with high risk of depression in patients with cervical cancer.
This study suggests that diabetes may be associated with a increased risk of high risk of depression in cervical cancer patients. Therefore, appropriate treatment of diabetes in cervical cancer patients may contribute to lowering the risk of depression in the future.
本研究的目的是评估韩国宫颈癌患者中抑郁症高风险与高血压、糖尿病和血脂异常等代谢性疾病之间的关联。
本研究纳入了330名宫颈癌女性患者,使用了2010年至2021年韩国国家健康与营养检查调查的数据。根据参与者对与抑郁症相关调查项目的回答,将其分为两组——抑郁症高风险组和非抑郁症组。采用多因素逻辑回归分析来评估代谢性疾病对宫颈癌患者抑郁症高风险的影响。
共有78名(23.64%)和252名(76.36%)女性分别被归类为抑郁症高风险组和非抑郁症组。在对年龄、绝经状态和吸烟状态进行调整的多因素逻辑回归分析中,糖尿病与宫颈癌患者抑郁症高风险的比值比为2.47(95%置信区间:1.205,5.071)。然而,在代谢性疾病中,高血压和血脂异常与宫颈癌患者抑郁症高风险无关。
本研究表明,糖尿病可能与宫颈癌患者抑郁症高风险的增加有关。因此,对宫颈癌患者的糖尿病进行适当治疗可能有助于降低未来抑郁症的风险。