病例报告：对伴有完全性AZFC微缺失和隐睾症的男性不育症进行综合评估与管理
Case report: Comprehensive evaluation and management of male infertility with complete AZFC microdeletion and undescended testicle.
作者信息
Turgut Niyazi Emre, Basar Mehmet Murad
机构信息
NESTA Clinic, Istanbul, Turkiye.
Private Practice, Istanbul, Turkiye.
出版信息
Urol Case Rep. 2025 Jan 7;59:102934. doi: 10.1016/j.eucr.2025.102934. eCollection 2025 Mar.
This case report presents a 31-year-old male patient with primary infertility, a unilaterally undescended testicle, and a complete AZFc microdeletion. Despite failed attempts at testicular sperm extraction, the patient underwent successful microscopic testicular sperm extraction and subsequent viable sperm extraction, leading to successful fertilization through intracytoplasmic sperm injection (ICSI). The report underscores the potential for successful ICSI in male infertility cases with complex genetic and reproductive issues, highlighting the importance of comprehensive genetic evaluation and individualized reproductive techniques in managing male infertility associated with undescended testicle and genetic anomalies.
本病例报告介绍了一名31岁的男性原发性不育患者，其一侧睾丸未降，并存在完全性AZFc微缺失。尽管睾丸精子提取尝试失败，但该患者成功接受了显微睾丸精子提取及随后的活精子提取，通过卵胞浆内单精子注射（ICSI）实现了成功受精。该报告强调了在患有复杂遗传和生殖问题的男性不育病例中ICSI成功的可能性，突出了全面遗传评估和个体化生殖技术在处理与睾丸未降和遗传异常相关的男性不育中的重要性。
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