Powe T A, Powers R D
J Am Vet Med Assoc. 1985 Mar 15;186(6):588-9.
Thirteen mixed-breed beef bulls, 1 to 4 years old, were used to determine the effect of live and dead filarial nematodes, Setaria labiatopapillosa, placed in the vaginal cavity of the testes. When dead worms were used, granulomatous lesions developed on the tunica vaginalis parietalis in 7 of 8 testes. The lesions were similar to those seen in some clinical cases of periorchitis. Similar lesions developed in 5 of 6 testes after live worms were implanted in the vaginal cavity of the testes and tetramisole (8 mg/kg) was injected subcutaneously 6 days after implantation. When live worms were implanted and tetramisole was not given, lesions developed in 3 of 6 testes. It was concluded that the granulomatous reaction was a local response to dead or killed S labiatopapillosa.
选用13头1至4岁的杂种肉用公牛，以确定将活的和死的丝状线虫——唇乳突丝虫（Setaria labiatopapillosa）置于睾丸阴道腔内所产生的影响。当使用死虫时，8个睾丸中的7个在睾丸鞘膜壁层上出现了肉芽肿性病变。这些病变与某些睾丸炎临床病例中所见的病变相似。在将活虫植入睾丸阴道腔并于植入后6天皮下注射四咪唑（8毫克/千克）后，6个睾丸中的5个出现了类似病变。当植入活虫且未给予四咪唑时，6个睾丸中有3个出现了病变。得出的结论是，肉芽肿反应是对死的或被杀灭的唇乳突丝虫的局部反应。
