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接受桡动脉冠状动脉造影患者的桡动脉血栓形成及相关危险因素

Radial Artery Thrombosis and Associated Risk Factors in Patients Undergoing Radial Coronary Angiography.

作者信息

Ay Esra Koc, Naldemir Ibrahim Feyyaz, Ozde Cem, Akture Gulsah, Aytekin Seda, Kayapinar Osman, Karaca Gürkan, Kimiaei Ali, Safaei Seyedehtina, Kaya Adnan

机构信息

Cardiology, Ödemiş State Hospital, Ödemiş, Turkey.

Radiology, Düzce University School of Medicine, Düzce, Turkey.

出版信息

Heart Int. 2024 Oct 21;18(2):37-43. doi: 10.17925/HI.2024.18.2.1. eCollection 2024.

DOI:10.17925/HI.2024.18.2.1
PMID:39885935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11781368/
Abstract

Radial access is considered the preferred method for coronary angiography (CAG) and percutaneous coronary intervention. Radial artery thrombosis (RAT) stands out as the primary complication associated with trans-radial access. Our objective was to explore the occurrence of RAT and its associated risk factors. A study encompassing 150 patients who underwent coronary interventions via radial access was conducted. Colour Doppler ultrasonography was used to assess proximal and distal radial flow rates 4-6 hours post-procedure. Patients diagnosed with RAT constituted the study group, while those without RAT were designated as controls. Among the 150 patients, 20 (13.3%) developed RAT, with partial occlusions observed in 2.7% and total occlusions in 10.7%. Univariate analysis identified potential correlations between RAT and variables such as female gender, hypertension (HT), history of coronary artery disease, use of anti-thrombocyte medications, duration of compression, indication for CAG, haematocrit levels, neutrophil count, creatinine levels and estimated glomerular filtration rate. However, only HT showed a statistically significant association. Multivariate analysis confirmed HT, anti-thrombocyte drug use, duration of compression, haematocrit levels and creatinine levels as independent predictors of RAT. HT, anti-thrombocyte drug use, duration of compression, haematocrit levels and creatinine levels are identified as independent predictors of RAT. Standard pulse examination may not adequately detect RAT.

摘要

桡动脉途径被认为是冠状动脉造影(CAG)和经皮冠状动脉介入治疗的首选方法。桡动脉血栓形成(RAT)是经桡动脉途径相关的主要并发症。我们的目的是探讨RAT的发生率及其相关危险因素。对150例经桡动脉途径进行冠状动脉介入治疗的患者进行了一项研究。在术后4 - 6小时使用彩色多普勒超声评估桡动脉近端和远端的血流速度。被诊断为RAT的患者构成研究组,未发生RAT的患者被指定为对照组。在这150例患者中,20例(13.3%)发生了RAT,其中部分闭塞占2.7%,完全闭塞占10.7%。单因素分析确定了RAT与女性性别、高血压(HT)、冠状动脉疾病史、抗血小板药物使用、压迫时间、CAG指征、血细胞比容水平、中性粒细胞计数、肌酐水平和估计肾小球滤过率等变量之间的潜在相关性。然而,只有HT显示出统计学上的显著关联。多因素分析证实HT、抗血小板药物使用、压迫时间、血细胞比容水平和肌酐水平是RAT的独立预测因素。HT、抗血小板药物使用、压迫时间、血细胞比容水平和肌酐水平被确定为RAT的独立预测因素。标准脉搏检查可能无法充分检测出RAT。

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J Cardiovasc Dev Dis. 2023 Jun 30;10(7):283. doi: 10.3390/jcdd10070283.
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Comparison of spasmolytic regimen for prevention of radial artery spasm during the distal radial approach: A single-center, randomized study.桡动脉远端入路时预防桡动脉痉挛的解痉方案比较:一项单中心随机研究。
Front Cardiovasc Med. 2023 Mar 1;10:1007147. doi: 10.3389/fcvm.2023.1007147. eCollection 2023.
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Novel oral anticoagulants in the treatment of radial artery occlusion.新型口服抗凝药治疗桡动脉闭塞
Catheter Cardiovasc Interv. 2021 Nov 15;98(6):1133-1137. doi: 10.1002/ccd.29771. Epub 2021 May 14.
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Distal Transradial Access for Coronary Angiography and Interventions.经桡动脉远端入路行冠状动脉造影及介入治疗。
Curr Probl Cardiol. 2021 Mar;46(3):100714. doi: 10.1016/j.cpcardiol.2020.100714. Epub 2020 Sep 25.
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Best Practices for the Prevention of Radial Artery Occlusion After Transradial Diagnostic Angiography and Intervention: An International Consensus Paper.经桡动脉行诊断性血管造影和介入术后预防桡动脉闭塞的最佳实践:国际共识文件。
JACC Cardiovasc Interv. 2019 Nov 25;12(22):2235-2246. doi: 10.1016/j.jcin.2019.07.043.
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Current approach to the diagnosis of atherosclerotic coronary artery disease: more questions than answers.当前动脉粥样硬化性冠状动脉疾病的诊断方法:问题多于答案。
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