Ferguson D C
J Am Vet Med Assoc. 1985 Apr 1;186(7):693-5.
A 3-year-old spayed female ferret was examined because of mild icterus and massive splenomegaly. Pancytopenia was diagnosed and was unaffected by blood transfusion or corticosteroid therapy. Splenectomy resulted in resolution of clinical signs, with survival up to 20 months after surgery. Histologic examination of the spleen revealed areas of splenic necrosis and severe extramedullary hematopoiesis. The final diagnosis, based on exclusion of other causes of splenomegaly and pancytopenia, was idiopathic hypersplenism.
一只3岁已绝育的雌性雪貂因轻度黄疸和脾脏巨大而接受检查。诊断为全血细胞减少症,输血或皮质类固醇治疗对此均无效果。脾切除术后临床症状消失,术后存活长达20个月。脾脏组织学检查显示脾坏死区域和严重的髓外造血。在排除脾肿大和全血细胞减少的其他病因后,最终诊断为特发性脾功能亢进。