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一例具有非典型特征的播散性类鼻疽罕见病例,可能与吸食邦戈烟/水烟管有关。

A Peculiar Case of Disseminated Melioidosis with Atypical Features Likely Linked to Bong/Water Pipe Use.

作者信息

Jang Kisen, Sharma Anmol

机构信息

Medical Division, Base Hospital Delhi Cantt, New Delhi, India.

出版信息

J Glob Infect Dis. 2024 Aug 7;16(4):183-185. doi: 10.4103/jgid.jgid_5_24. eCollection 2024 Oct-Dec.

DOI:10.4103/jgid.jgid_5_24
PMID:39886090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11775393/
Abstract

Melioidosis, caused by , is a challenging infectious disease with global implications, primarily affecting Southeast Asia. We present the case of a 24-year-old male with a curious history of tobacco use, presenting with fevers, weight loss, and genitourinary symptoms. Diagnostic challenges arose as symptoms mimicked other diseases. Disseminated melioidosis was confirmed via Gram staining and positron emission tomography scan findings, emphasizing the disease's diverse clinical manifestations. Treatment with ceftazidime and cotrimoxazole led to prompt recovery. Notably, the patient's tobacco use linked to contaminated water highlights a unique transmission route. This case underscores the need for heightened awareness and preventive measures in endemic regions.

摘要

类鼻疽病由(此处原文缺失病原体信息)引起,是一种具有全球影响的具有挑战性的传染病,主要影响东南亚地区。我们报告一例24岁男性病例,该患者有奇特的烟草使用史,出现发热、体重减轻和泌尿生殖系统症状。由于症状与其他疾病相似,诊断面临挑战。通过革兰氏染色和正电子发射断层扫描结果确诊为播散性类鼻疽病,这凸显了该疾病多样的临床表现。使用头孢他啶和复方新诺明治疗后患者迅速康复。值得注意的是,患者的烟草使用与受污染水有关,这突出了一种独特的传播途径。该病例强调了在流行地区提高认识和采取预防措施的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/3f6fd9160c6d/JGID-16-183-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/483d0da18362/JGID-16-183-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/8919624ba102/JGID-16-183-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/892d43af22b8/JGID-16-183-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/3f6fd9160c6d/JGID-16-183-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/483d0da18362/JGID-16-183-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/8919624ba102/JGID-16-183-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/892d43af22b8/JGID-16-183-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd78/11775393/3f6fd9160c6d/JGID-16-183-g004.jpg

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本文引用的文献

1
Burden of melioidosis in India and South Asia: Challenges and ways forward.印度和南亚类鼻疽病的负担:挑战与未来之路
Lancet Reg Health Southeast Asia. 2022 May 5;2:100004. doi: 10.1016/j.lansea.2022.03.004. eCollection 2022 Jul.
2
The Epidemiology of Melioidosis and Its Association with Diabetes Mellitus: A Systematic Review and Meta-Analysis.类鼻疽的流行病学及其与糖尿病的关联:一项系统评价和荟萃分析。
Pathogens. 2022 Jan 25;11(2):149. doi: 10.3390/pathogens11020149.
3
Case Report: Imported Melioidosis from Goa, India to Israel, 2018.
病例报告:2018 年,印度果阿输入性类鼻疽病至以色列。
Am J Trop Med Hyg. 2019 Sep;101(3):580-584. doi: 10.4269/ajtmh.19-0303.
4
Melioidosis in South Asia (India, Nepal, Pakistan, Bhutan and Afghanistan).南亚(印度、尼泊尔、巴基斯坦、不丹和阿富汗)的类鼻疽病。
Trop Med Infect Dis. 2018 May 22;3(2):51. doi: 10.3390/tropicalmed3020051.
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Melioidosis.类鼻疽病。
Nat Rev Dis Primers. 2018 Feb 1;4:17107. doi: 10.1038/nrdp.2017.107.
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The epidemiology and clinical spectrum of melioidosis in a teaching hospital in a North-Eastern state of Malaysia: a fifteen-year review.马来西亚东北部某教学医院类鼻疽的流行病学及临床谱:一项十五年回顾
BMC Infect Dis. 2016 Jul 16;16:333. doi: 10.1186/s12879-016-1583-2.
7
Pitfalls and optimal approaches to diagnose melioidosis.诊断类鼻疽病的陷阱和最佳方法。
Asian Pac J Trop Med. 2016 Jun;9(6):515-24. doi: 10.1016/j.apjtm.2016.04.003. Epub 2016 Apr 29.
8
Melioidosis caused by Burkholderia pseudomallei in drinking water, Thailand, 2012.2012年,泰国饮用水中由类鼻疽伯克霍尔德菌引起的类鼻疽病。
Emerg Infect Dis. 2014 Feb;20(2):265-8. doi: 10.3201/eid2002.121891.