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新生儿自发性肾上腺出血:一例报告

Spontaneous adrenal hemorrhage in a newborn: a case report.

作者信息

Lodhia Jay, Sikobizahora Sophie, Gondwe Stephen, Philemon Rune Nathaniel

机构信息

Department of General Surgery, Kilimanjaro Christian Medical Centre, P.O Box 3010, Moshi, Tanzania.

Kilimanjaro Christian Medical University College, Faculty of Medicine, P.O Box 2240, Moshi, Tanzania.

出版信息

Pan Afr Med J. 2024 Oct 13;49:39. doi: 10.11604/pamj.2024.49.39.44725. eCollection 2024.

DOI:10.11604/pamj.2024.49.39.44725
PMID:39886115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11781211/
Abstract

Neonatal adrenal hemorrhage is a rare condition with various risk factors in the pediatric population. Adrenal hemorrhage commonly affects the right side in about 70% of the cases and bilateral in about 10%. It is usually asymptomatic but can cause adrenal insufficiency and sudden death. Neonatal adrenal hemorrhage should be considered even when there are no risk factors, as it can occur spontaneously with unspecific clinical presentations. Ultrasonography can confirm diagnosis, a relatively cheap and safe modality, especially for resource-limited settings. In this case report, we present a two-day-old with progressive scrotal hematoma and inguinal ecchymosis with no risk factors. Magnetic resonance imaging confirmed right adrenal hemorrhage; however, the newborn deteriorated fast, reaching mortality within 24 hours of admission. This case illustrates the importance of recognizing the condition to allow for an evidenced approach, which may include conservative waiting, as unwarranted intervention can have negative outcomes.

摘要

新生儿肾上腺出血是儿科人群中一种罕见的病症,存在多种风险因素。肾上腺出血在约70%的病例中通常累及右侧,约10%为双侧受累。它通常无症状,但可导致肾上腺功能不全和猝死。即使没有风险因素也应考虑新生儿肾上腺出血,因为它可无特异性临床表现而自发发生。超声检查可确诊,这是一种相对便宜且安全的检查方式,尤其适用于资源有限的环境。在本病例报告中,我们呈现了一名两天大的婴儿,无风险因素却出现进行性阴囊血肿和腹股沟瘀斑。磁共振成像证实为右侧肾上腺出血;然而,新生儿病情迅速恶化,入院后24小时内死亡。本病例说明了认识该病症以便采取循证方法的重要性,这可能包括保守观察,因为不必要的干预可能会产生负面结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e353/11781211/119fc0961b12/PAMJ-49-39-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e353/11781211/0a621e88fd93/PAMJ-49-39-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e353/11781211/119fc0961b12/PAMJ-49-39-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e353/11781211/0a621e88fd93/PAMJ-49-39-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e353/11781211/119fc0961b12/PAMJ-49-39-g002.jpg

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1
Spontaneous adrenal hemorrhage in a newborn: a case report.新生儿自发性肾上腺出血:一例报告
Pan Afr Med J. 2024 Oct 13;49:39. doi: 10.11604/pamj.2024.49.39.44725. eCollection 2024.
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Neonatal adrenal haemorrhage with contralateral scrotal haematoma and inguinal ecchymosis.新生儿肾上腺出血伴对侧阴囊血肿和腹股沟瘀斑。
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Neonatal adrenal hemorrhage presenting as scrotal hematoma.表现为阴囊血肿的新生儿肾上腺出血。
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4
Acute scrotal swelling: a sign of neonatal adrenal haemorrhage.急性阴囊肿胀:新生儿肾上腺出血的一种体征。
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Scrotal hematoma as a sign of adrenal hemorrhage in newborns.阴囊血肿作为新生儿肾上腺出血的一种体征。
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Adrenal hemorrhage presenting as a scrotal hematoma in the newborn: A case report.新生儿肾上腺出血表现为阴囊血肿:一例报告。
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[Neonatal adrenal hemorrhage associated with a scrotal hematoma. A case report].[新生儿肾上腺出血伴阴囊血肿。病例报告]
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本文引用的文献

1
Neonatal massive adrenal hemorrhage with scrotal hematoma progressing to hypovolemic shock.新生儿大量肾上腺出血伴阴囊血肿进展为低血容量性休克。
Pediatr Neonatol. 2023 Jul;64(4):472-473. doi: 10.1016/j.pedneo.2022.12.006. Epub 2023 Jan 27.
2
Neonatal adrenal hemorrhage presenting as an acute scrotum: A case report on the rare presentation of right adrenal hemorrhage and contralateral left scrotal hematoma.表现为急性阴囊的新生儿肾上腺出血:一例罕见的右侧肾上腺出血及对侧左侧阴囊血肿病例报告
IJU Case Rep. 2022 Jun 16;5(6):427-430. doi: 10.1002/iju5.12495. eCollection 2022 Nov.
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Neonatal bilateral adrenal hemorrhage and adrenal insufficiency accompanied by Subgaleal hematoma: a case report with brief review of literature.
新生儿双侧肾上腺出血伴肾上腺功能不全合并帽状腱膜下血肿:病例报告并文献复习
BMC Pediatr. 2022 May 5;22(1):248. doi: 10.1186/s12887-022-03314-1.
4
Bilateral Neonatal Adrenal Hemorrhage Associated With Severe Maternal COVID-19 Infection.与严重母体新冠病毒感染相关的双侧新生儿肾上腺出血
Cureus. 2021 Nov 29;13(11):e20007. doi: 10.7759/cureus.20007. eCollection 2021 Nov.
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Adrenal hemorrhage and hemorrhagic masses; diagnostic workup and imaging findings.肾上腺出血和出血性肿块;诊断方法和影像学表现。
Br J Radiol. 2021 Nov 1;94(1127):20210753. doi: 10.1259/bjr.20210753. Epub 2021 Aug 31.
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Neonatal Adrenal Hemorrhage: A Case Series.新生儿肾上腺出血:病例系列
Am J Perinatol. 2020 Sep;37(S 02):S57-S60. doi: 10.1055/s-0040-1713407. Epub 2020 Sep 8.
7
Adrenal hemorrhage in newborn: how, when and why- from case report to literature review.新生儿肾上腺出血:从病例报告到文献综述——如何、何时以及为何。
Ital J Pediatr. 2019 May 8;45(1):58. doi: 10.1186/s13052-019-0651-9.
8
Adrenal insufficiency.肾上腺功能不全
Pediatr Rev. 2015 Mar;36(3):92-102; quiz 103, 129. doi: 10.1542/pir.36-3-92.
9
Neonatal adrenal hemorrhage associated with scrotal hematoma: an unusual case report and literature review.新生儿肾上腺出血合并阴囊血肿:一例不寻常病例报告及文献复习。
Pediatr Neonatol. 2012 Jun;53(3):210-2. doi: 10.1016/j.pedneo.2012.04.010. Epub 2012 Jun 12.