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聚焦心脏:借助床旁超声推进心包积液诊断

Heart in Focus: Advancing Pericardial Effusion Diagnosis With Point-of-Care Ultrasound.

作者信息

Moura de Azevedo Sofia, Duarte Rodrigo, Krowicki Jéssica, Vázquez Dolores, Pires Ferreira Arroja Sheila, Mariz José

机构信息

Internal Medicine, Centro Hospitalar Universitário de Santo António, Porto, PRT.

Internal Medicine, Centro Hospitalar de Lisboa Ocidental, Lisbon, PRT.

出版信息

Cureus. 2024 Dec 31;16(12):e76681. doi: 10.7759/cureus.76681. eCollection 2024 Dec.

DOI:10.7759/cureus.76681
PMID:39886707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11781757/
Abstract

Pericardial effusion refers to the accumulation of fluid within the pericardial sac, the double-layered membrane surrounding the heart. It can be caused by various medical conditions and may lead to serious complications if not diagnosed and managed promptly. Point-of-care ultrasound (POCUS) has emerged as a valuable tool in the clinical evaluation of pericardial effusions, offering real-time visualization and aiding in the assessment of its size, characteristics, and potential hemodynamic impact. This comprehensive revision explores the utility of POCUS in diagnosing and managing pericardial effusions. POCUS has gained prominence as a bedside diagnostic tool due to its immediacy, accuracy, and non-invasive nature. This study investigates how POCUS can address critical gaps in current diagnostic approaches, such as delays in diagnosis using traditional imaging modalities and challenges in resource-limited settings, thereby enhancing patient outcomes and clinical decision-making. A search was conducted on PubMed in August of 2023, using the keywords "POCUS" and "pericardial" as MeSH terms and reference mining. A total of 19 articles were included in this review. Characterization and quantification of pericardial effusion (PEF) using POCUS can provide clinicians with critical clues regarding the underlying etiology. This information, combined with other hemodynamic parameters, should guide subsequent management decisions. POCUS enables the identification of key sonographic findings, such as diastolic collapse of the right chambers, abnormal septal movement, and an engorged inferior vena cava (IVC), which together raise a high clinical suspicion of cardiac tamponade. Beyond its utility in identifying tamponade, POCUS plays a significant role in detecting subtle yet life-threatening conditions, such as aortic dissection, which may manifest as pericardial effusion due to hemopericardium. While POCUS is not definitive for diagnosing aortic dissection, indirect findings such as a pericardial effusion with hemodynamic compromise, coupled with high clinical suspicion, should prompt further imaging like CT angiography for confirmation. We propose an algorithmic approach: if cardiac tamponade is confirmed on POCUS, emergent pericardiocentesis is warranted. If ruled out, further investigations should be directed toward identifying the underlying cause of the PEF, including potentially ruling out aortic dissection to avoid missing a subtle but critical condition. POCUS has revolutionized the clinical evaluation of pericardial effusions, providing clinicians with a rapid and accurate bedside tool for diagnosis and management. Its ability to assess effusion size, identify cardiac tamponade, and guide pericardiocentesis procedures has proven invaluable in improving patient outcomes. Integrating POCUS into routine clinical practice enhances diagnostic accuracy and timely intervention, ensuring better care for patients with pericardial effusions. However, it is important to acknowledge its limitations. POCUS is highly operator-dependent, with diagnostic accuracy varying based on the clinician's experience and training. Additionally, the availability of ultrasound equipment and adequately trained personnel can be a barrier, particularly in resource-limited settings. Addressing these challenges is crucial to maximizing the utility of POCUS in clinical practice.

摘要

心包积液是指心包腔内(围绕心脏的双层膜)液体的积聚。它可由多种医疗状况引起,如果不及时诊断和处理,可能会导致严重并发症。床旁超声(POCUS)已成为心包积液临床评估中的一种重要工具,可提供实时可视化图像,并有助于评估积液的大小、特征及其潜在的血流动力学影响。本全面综述探讨了POCUS在诊断和处理心包积液方面的实用性。由于其即时性、准确性和非侵入性,POCUS已成为一种重要的床旁诊断工具。本研究调查了POCUS如何弥补当前诊断方法中的关键不足,例如使用传统成像方式时的诊断延迟以及资源有限环境中的挑战,从而改善患者预后并提升临床决策水平。2023年8月在PubMed上进行了检索,使用关键词“POCUS”和“心包”作为医学主题词并进行参考文献挖掘。本综述共纳入19篇文章。使用POCUS对心包积液(PEF)进行特征描述和定量分析可为临床医生提供有关潜在病因的关键线索。这些信息与其他血流动力学参数相结合,应指导后续的管理决策。POCUS能够识别关键的超声检查结果,如右心房舒张期塌陷、室间隔运动异常以及下腔静脉(IVC)扩张,这些共同提示高度怀疑心脏压塞。除了在识别心脏压塞方面的作用外,POCUS在检测细微但危及生命的状况(如主动脉夹层)方面也发挥着重要作用,主动脉夹层可能因心包积血而表现为心包积液。虽然POCUS对诊断主动脉夹层并不具有决定性,但如心包积液伴血流动力学受损等间接发现,再加上高度的临床怀疑,应促使进一步进行如CT血管造影等影像学检查以确诊。我们提出一种算法方法:如果POCUS确诊为心脏压塞,则有必要紧急进行心包穿刺术。如果排除心脏压塞,则应进一步检查以确定PEF的潜在病因,包括可能排除主动脉夹层,以避免漏诊细微但关键的病情。POCUS彻底改变了心包积液的临床评估,为临床医生提供了一种快速准确的床旁诊断和管理工具。其评估积液大小、识别心脏压塞以及指导心包穿刺术的能力已被证明在改善患者预后方面具有不可估量的价值。将POCUS纳入常规临床实践可提高诊断准确性并实现及时干预,确保为心包积液患者提供更好的治疗。然而,必须认识到其局限性。POCUS高度依赖操作者,诊断准确性因临床医生的经验和培训而异。此外,超声设备和训练有素的人员的可获得性可能是一个障碍,特别是在资源有限的环境中。应对这些挑战对于在临床实践中最大限度地发挥POCUS的作用至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7283/11781757/754a2318dfc5/cureus-0016-00000076681-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7283/11781757/754a2318dfc5/cureus-0016-00000076681-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7283/11781757/754a2318dfc5/cureus-0016-00000076681-i01.jpg

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本文引用的文献

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ED point-of-care ultrasonography is associated with earlier drainage of pericardial effusion: A retrospective cohort study.床边即时超声心动图与心包积液的早期引流相关:一项回顾性队列研究。
Am J Emerg Med. 2022 Oct;60:156-163. doi: 10.1016/j.ajem.2022.08.008. Epub 2022 Aug 8.
2
Pericardial tamponade: A comprehensive emergency medicine and echocardiography review.心包填塞:综合急救医学与超声心动图复习
Am J Emerg Med. 2022 Aug;58:159-174. doi: 10.1016/j.ajem.2022.05.001. Epub 2022 May 6.
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IVC measurement for the noninvasive evaluation of central venous pressure.
测量下腔静脉内径用于评估中心静脉压(非侵入性方法)。
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Australas J Ultrasound Med. 2018 Feb 28;21(2):79-86. doi: 10.1002/ajum.12086. eCollection 2018 May.
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Ultrasound J. 2021 Feb 4;13(1):2. doi: 10.1186/s13089-021-00205-x.
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Focused assessment with sonography in trauma (FAST) for the regional anesthesiologist and pain specialist.创伤超声重点评估(FAST)在区域麻醉师和疼痛专家中的应用。
Reg Anesth Pain Med. 2019 May;44(5):540-548. doi: 10.1136/rapm-2018-100312. Epub 2019 Mar 21.
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What echocardiographic findings suggest a pericardial effusion is causing tamponade?哪些超声心动图发现提示心包积液导致了心脏压塞?
Am J Emerg Med. 2019 Feb;37(2):321-326. doi: 10.1016/j.ajem.2018.11.004. Epub 2018 Nov 17.
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The Practice and Implications of Finding Fluid During Point-of-Care Ultrasonography: A Review.即时超声检查中发现液体的实践与意义:综述
JAMA Intern Med. 2017 Dec 1;177(12):1818-1825. doi: 10.1001/jamainternmed.2017.5048.
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Emergency department point-of-care ultrasonography improves time to pericardiocentesis for clinically significant effusions.急诊科即时超声检查可缩短对具有临床意义的心包积液进行心包穿刺术的时间。
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Internal Medicine Point-of-Care Ultrasound Curriculum: Consensus Recommendations from the Canadian Internal Medicine Ultrasound (CIMUS) Group.内科学即时超声课程:来自加拿大内科学超声(CIMUS)小组的共识推荐。
J Gen Intern Med. 2017 Sep;32(9):1052-1057. doi: 10.1007/s11606-017-4071-5. Epub 2017 May 11.