Fremlin Kate M, Elliott John E, Gobas Frank A P C
Department of Biological Sciences, Simon Fraser University, Burnaby, BC, Canada.
Ecotoxicology and Wildlife Health Division, Environment and Climate Change Canada, Delta, BC, Canada.
Integr Environ Assess Manag. 2025 Mar 1;21(2):263-278. doi: 10.1093/inteam/vjae025.
As field based trophic magnification factors (TMFs) and biomagnification factors (BMFs) become more prominent regulatory metrics used in bioaccumulation assessments of commercial chemicals, there is a need to develop standardized guidelines for conducting field-based bioaccumulation studies and to establish methods using weight of evidence analyses of those studies. Hence, the primary objectives of this study were (1) to compile a set of comprehensive criteria and guidelines for conducting field-based biomagnification studies and (2) to develop a weight of evidence meta-analysis for evaluating field-based biomagnification studies and their reported biomagnification metrics for assessing the biomagnification potential of substances. To test the effectiveness of our proposed guidelines and weight of evidence meta-analysis, we reviewed over 25 field studies investigating the biomagnification of decabromodiphenyl ethane (DBDPE), a substance that is considered super-hydrophobic and difficult to test in bioconcentration tests. Approximately half of the field studies that investigated trophic magnification of DBDPE in food webs or biomagnification of DBDPE in predator-prey interactions were considered of acceptable quality, whereas no studies were of high quality. Quality scores of studies statistically decreased with increasing TMF (r2 = 0.261, p = .035) and/or BMF (r2 = 0.238, p = .0024). The weight of evidence meta-analysis indicated with a high level of confidence that concentrations of DBDPE do not biomagnify in top predators and within food-webs. Given the increasing importance of the TMF and BMF for bioaccumulation assessments and the apparent deficiencies in current biomagnification studies identified in this meta-analysis for DBDPE, there is an urgent need to adopt standardized guidelines and procedures for both conducting and evaluating field-based biomagnification studies.
随着基于野外的营养放大因子（TMFs）和生物放大因子（BMFs）在商业化学品生物累积评估中成为更为突出的监管指标，有必要制定用于开展基于野外的生物累积研究的标准化指南，并建立利用这些研究的证据权重分析的方法。因此，本研究的主要目标是：（1）编制一套用于开展基于野外的生物放大研究的综合标准和指南；（2）开发一种证据权重元分析方法，用于评估基于野外的生物放大研究及其报告的生物放大指标，以评估物质的生物放大潜力。为了测试我们提出的指南和证据权重元分析的有效性，我们回顾了25多项关于十溴二苯醚（DBDPE）生物放大的野外研究，DBDPE是一种被认为具有超疏水性且难以在生物浓缩试验中进行测试的物质。在调查食物网中DBDPE的营养放大或捕食者 - 猎物相互作用中DBDPE的生物放大的野外研究中，约有一半被认为质量可接受，而没有高质量的研究。研究的质量得分随着TMF（r2 = 0.261，p = 0.035）和/或BMF（r2 = 0.238，p = 0.0024）的增加而在统计学上降低。证据权重元分析高度确信地表明，DBDPE的浓度在顶级捕食者和食物网中不会生物放大。鉴于TMF和BMF在生物累积评估中的重要性日益增加，以及本元分析中确定的当前生物放大研究中存在的明显不足，迫切需要采用标准化的指南和程序来开展和评估基于野外的生物放大研究。
