是时候关注家庭照顾者对癌症复发的恐惧了：针对家庭照顾者版本的复发恐惧疗法（FC-FORT）的随机试点研究的可行性和可接受性。

It is Time to Address Fear of Cancer Recurrence in Family Caregivers: Feasibility and Acceptability of a Randomized Pilot Study of the Family Caregiver Version of the Fear of Recurrence Therapy (FC-FORT).

作者信息

Lamarche Jani, Nissim Rinat, Avery Jonathan, Wong Jiahui, Maheu Christine, Lambert Sylvie D, Laizner Andrea M, Jones Jennifer, Esplen Mary Jane, Lebel Sophie

机构信息

School of Psychology, University of Ottawa, Ottawa, Canada.

Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.

出版信息

Psychooncology. 2025 Feb;34(2):e70084. doi: 10.1002/pon.70084.

DOI:10.1002/pon.70084

PMID:39887474

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11779570/

Abstract

OBJECTIVE

Fear of cancer recurrence (FCR) is common, persistent, and associated with lower quality of life, impaired functioning, and psychological distress in family caregivers (FC) of individuals with a cancer diagnosis. Interventions are needed to specifically target FCR in FC. This study aimed to pilot test the adapted Family Caregiver-Fear Of Recurrence Therapy (FC-FORT) to establish its feasibility, acceptability, and clinical significance.

METHODS

This pilot study used a mixed-method, parallel, two-group randomized control trial (FC-FORT vs. waitlist control group) design. Women FC were recruited through Canadian hospitals, community partners, and social media. FC in the intervention group completed 7 weekly sessions of virtual group therapy (FC-FORT) and an exit interview. All participants completed questionnaires at baseline, post-intervention, and 3-month follow-up. Feasibility (e.g., recruitment, allocation, fidelity), acceptability (e.g., dropout, completion, satisfaction) and clinical significance of secondary outcomes were evaluated. Descriptive statistics, mixed ANOVAs, and conventional content analyses were used.

RESULTS

Regarding feasibility, 22 FC were recruited, 18 were randomized and therapist fidelity was 87%. As to acceptability, 67% of participants completed 5 sessions (33% dropout). Questionnaire completion rate was 92%. FC satisfaction was 80%. Analyses did not reveal any significant differences on the secondary outcomes between groups. Qualitative analyses revealed high importance, helpfulness, satisfaction, and group cohesion. Suggestions were made by FC for improvements.

CONCLUSIONS

This is one of the first interventions to address FCR in FC. While acceptability of FC-FORT was good, important feasibility issues need to be addressed before moving forward with a larger randomized control trial.

TRIAL REGISTRATION

NCT, NCT05441384. Registered July 1st, 2022, https://classic.

CLINICALTRIALS

gov/ct2/show/NCT05441384.

摘要

目的

癌症复发恐惧（FCR）很常见且持续存在，与癌症诊断患者的家庭照顾者（FC）生活质量较低、功能受损及心理困扰相关。需要针对家庭照顾者的癌症复发恐惧进行专门干预。本研究旨在对改编后的家庭照顾者-癌症复发恐惧疗法（FC-FORT）进行试点测试，以确定其可行性、可接受性和临床意义。

方法

本试点研究采用混合方法、平行、两组随机对照试验（FC-FORT组与等待列表对照组）设计。通过加拿大医院、社区合作伙伴和社交媒体招募女性家庭照顾者。干预组的家庭照顾者完成了7次每周一次的虚拟团体治疗（FC-FORT）和一次退出访谈。所有参与者在基线、干预后和3个月随访时完成问卷。评估了可行性（如招募、分配、保真度）、可接受性（如退出、完成、满意度）以及次要结局的临床意义。使用描述性统计、混合方差分析和传统内容分析。

结果

在可行性方面，招募了22名家庭照顾者，18名被随机分组，治疗师保真度为87%。在可接受性方面，67%的参与者完成了5次治疗（33%退出）。问卷完成率为92%。家庭照顾者满意度为80%。分析未发现两组在次要结局上有任何显著差异。定性分析显示高度重视、有帮助、满意度高且团体凝聚力强。家庭照顾者提出了改进建议。