Ma Yunfei, Wang Songtao, Sun Wei, Zhou Longlong, Deng Yiqing, Zhao Qiang
School of Chemical Engineering, Sichuan University, Chengdu, Sichuan, China.
College of Polymer Science and Engineering, Sichuan University, Chengdu, Sichuan, China.
Luminescence. 2025 Feb;40(2):e70113. doi: 10.1002/bio.70113.
Copper ions (Cu) play a crucial role in biological processes; however, excessive intake can result in severe health problems. Current methods for detecting copper ions are both expensive and complex. Therefore, there is a need for efficient and straightforward visual detection methods. In this study, novel nitrogen-doped carbon dots (N-CDs) were synthesized via a microchannel method using diethylenetriamine and citric acid as precursors and were characterized by TEM, XRD, and IR, among others. The N-CDs demonstrated high selectivity and strong fluorescence, showing a linear quenching response to copper ions with a detection limit of 46 nM, whereas other common metal ions, such as Ca and Mg, exhibited negligible interference even at higher concentrations. These N-CDs were subsequently applied to test paper, allowing for on-site visual and quantitative detection of copper ions via a colorimetric method. This approach provides a novel solution for the rapid detection of copper ions, with significant potential in environmental monitoring, public health, and industrial applications.
铜离子(Cu)在生物过程中起着至关重要的作用;然而,过量摄入会导致严重的健康问题。目前检测铜离子的方法既昂贵又复杂。因此,需要高效且简便的视觉检测方法。在本研究中,以二乙烯三胺和柠檬酸为前驱体,通过微通道法合成了新型氮掺杂碳点(N-CDs),并通过透射电子显微镜(TEM)、X射线衍射(XRD)和红外光谱(IR)等进行了表征。N-CDs表现出高选择性和强荧光,对铜离子呈现线性猝灭响应,检测限为46 nM,而其他常见金属离子,如Ca和Mg,即使在较高浓度下也表现出可忽略不计的干扰。这些N-CDs随后被应用于试纸,通过比色法实现了铜离子的现场视觉和定量检测。该方法为铜离子的快速检测提供了一种新的解决方案,在环境监测、公共卫生和工业应用中具有巨大潜力。