Moses Eleanor, Scambler Jenna, Taubert Jessica, Lo Ada H Y, Thompson Kate, de Gelder Beatrice, Pegna Alan J
School of Psychology, The University of Queensland, St Lucia, Queensland 4067, Australia.
Department of Psychology, Queensland Health, Brisbane, Queensland 4000, Australia.
eNeuro. 2025 Feb 14;12(2). doi: 10.1523/ENEURO.0114-24.2024. Print 2025 Feb.
The amygdala is believed to make invaluable contributions to visual emotion processing. Yet how this subcortical body contributes to emotion perception across time is contended. Here, we measured differences in the perceptual processing of emotional stimuli after unilateral temporal lobe and amygdala resection (TLR) in humans, using EEG. Through mass univariate analysis of brain activity, we compared responses to fearful and neutral faces (left TLR = 8, right TLR = 8, control = 8), and fearful and neutral bodies (left TLR = 9, right TLR = 9, control = 9). We found that TLR impaired the early-stage perceptual processing of emotional stimuli seen in the control group. Indeed, in controls a heightened responses to fearful faces was found in the 140-170 ms time window, over temporoparietal electrodes. This effect was also present in the left TLR group but disappeared in the right TLR group. For emotional bodies, brain activity was differentially sensitive to fearful stimuli at 90-120 ms in the control group, but this effect was eliminated in both TLR groups. Collectively, these results reveal the amygdala contributes to the early stages of perceptual processing that discriminate emotional stimuli from neutral stimuli. Further, they emphasize the unique role of the right medial temporal structures such as the amygdala in emotional face perception.
杏仁核被认为对视觉情绪处理做出了不可估量的贡献。然而，这个皮层下结构如何随时间对情绪感知产生影响仍存在争议。在这里，我们使用脑电图测量了人类单侧颞叶和杏仁核切除术后（TLR）情绪刺激的感知处理差异。通过对大脑活动的大规模单变量分析，我们比较了对恐惧和中性面孔（左TLR = 8，右TLR = 8，对照组 = 8）以及恐惧和中性身体（左TLR = 9，右TLR = 9，对照组 = 9）的反应。我们发现，TLR损害了对照组中所见情绪刺激的早期感知处理。事实上，在对照组中，在140 - 170毫秒的时间窗口内，颞顶电极上对恐惧面孔的反应增强。这种效应在左TLR组中也存在，但在右TLR组中消失。对于情绪身体，对照组在90 - 120毫秒时大脑活动对恐惧刺激有不同的敏感性，但在两个TLR组中这种效应都消失了。总体而言，这些结果表明杏仁核对将情绪刺激与中性刺激区分开来的感知处理早期阶段有贡献。此外，它们强调了右侧内侧颞叶结构如杏仁核在情绪面孔感知中的独特作用。
