Wyatt R D, Neathery M W, Moos W H, Miller W J, Gentry R P, Ware G O
J Dairy Sci. 1985 Feb;68(2):437-42. doi: 10.3168/jds.S0022-0302(85)80842-0.
Young male Holstein calves were fed diets containing 40 or 640 ppm zinc with 0 or 5 ppm aflatoxin for 3 wk. The aflatoxin mixture contained 80.5% B1 and the calves consumed 143 mg of B1 over 3 wk. Plasma glutamic-oxaloacetic transaminase and alkaline phosphatase concentrations were increased substantially, and lactic dehydrogenase was reduced in aflatoxin-fed calves. Supplemental zinc partially counteracted the effect of aflatoxin on these enzymes. Hemoglobin, packed cell volume, and total solids in blood plasma were increased in aflatoxin-fed calves, but high dietary zinc had no effect on these blood constituents. Glucose in plasma was reduced in calves receiving aflatoxin. High dietary zinc was only partially effective in protecting against the reduced glucose effect for about 1 wk. Total protein, albumin, globulin, ratio of albumin/globulin in blood plasma, and liver lipid were not affected by aflatoxin. Several enzymes and blood constituents are affected by aflatoxin in calves. The protection of zinc against aflatoxicosis appears to be no more than a partial effect.
将年轻的雄性荷斯坦犊牛饲喂含40或640 ppm锌且添加0或5 ppm黄曲霉毒素的日粮，持续3周。黄曲霉毒素混合物中B1含量为80.5%，犊牛在3周内摄入了143 mg的B1。饲喂黄曲霉毒素的犊牛血浆谷草转氨酶和碱性磷酸酶浓度大幅升高，乳酸脱氢酶降低。补充锌可部分抵消黄曲霉毒素对这些酶的影响。饲喂黄曲霉毒素的犊牛血红蛋白、红细胞压积和血浆总固体含量增加，但高锌日粮对这些血液成分没有影响。摄入黄曲霉毒素的犊牛血浆葡萄糖降低。高锌日粮在约1周内仅部分有效地防止了葡萄糖降低的影响。血浆总蛋白、白蛋白、球蛋白、白蛋白/球蛋白比值和肝脏脂质不受黄曲霉毒素影响。黄曲霉毒素会影响犊牛的几种酶和血液成分。锌对黄曲霉毒素中毒的保护作用似乎只是部分有效。
