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解决非洲慢性创伤性脑病研究的不足:呼吁紧急关注。

Addressing the deficit in chronic traumatic encephalopathy research in Africa: a call for urgent attention.

作者信息

Muili Abdulbasit Opeyemi, Alare Kehinde, Solagbade Oluwapelumi Samuel, Kuol Piel Panther

机构信息

Department of Medicine, Ladoke Akintola University of Technology, Ogbomosho, Nigeria.

Department of Medicine and Surgery, Obafemi Awolowo University, Ife, Nigeria.

出版信息

Chin Neurosurg J. 2025 Feb 1;11(1):2. doi: 10.1186/s41016-025-00388-5.

DOI:10.1186/s41016-025-00388-5
PMID:39891236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11786488/
Abstract

Chronic traumatic Encephalopathy (CTE) has been linked to an increase in the mortality of contact sport athletes in the USA, most especially in the early 2000s due to limited information on its existence. The lack of understanding of its existence resulted in delayed diagnosis and inadequate treatment of the disease for affected individuals.Africa faces a similar gap as awareness and research on CTE remain limited in the region where active participation in contact sports is rising. If no drastic action is taken to mitigate the gap, the region may face similar health consequences in the future.Various challenges responsible for the gap can be attributed to limited infrastructure, limited funding opportunities, and sociocultural factors. To address these challenges, a multifaceted approach is necessary through increasing funding, integrating CTE education into the medical curriculum, improving infrastructure, and resolving sociocultural myths about organ donation.

摘要

慢性创伤性脑病(CTE)与美国接触性运动运动员死亡率上升有关,尤其是在21世纪初,因为当时关于其存在的信息有限。对其存在缺乏了解导致受影响个体的疾病诊断延迟和治疗不足。非洲也面临类似的差距,因为在该地区,尽管参与接触性运动的人数不断增加,但对CTE的认识和研究仍然有限。如果不采取严厉措施来缩小这一差距,该地区未来可能面临类似的健康后果。造成这一差距的各种挑战可归因于基础设施有限、资金机会有限和社会文化因素。为应对这些挑战,有必要采取多方面的方法,包括增加资金、将CTE教育纳入医学课程、改善基础设施以及消除关于器官捐赠的社会文化误解。

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本文引用的文献

1
Concussion-Related Biomarker Variations in Retired Rugby Players and Implications for Neurodegenerative Disease Risk: The UK Rugby Health Study.退役橄榄球运动员与脑震荡相关生物标志物的变化及其对神经退行性疾病风险的影响:英国橄榄球健康研究。
Int J Mol Sci. 2024 Jul 17;25(14):7811. doi: 10.3390/ijms25147811.
2
Cultural practices of the Zulu ethnic group on the body and their influence on body donation.祖鲁族的身体文化习俗及其对器官捐献的影响。
Anat Sci Educ. 2020 Nov;13(6):721-731. doi: 10.1002/ase.1950. Epub 2020 Mar 3.
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The neuropathology of chronic traumatic encephalopathy.慢性创伤性脑病的神经病理学
Handb Clin Neurol. 2018;158:297-307. doi: 10.1016/B978-0-444-63954-7.00028-8.
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Transplantation in Africa - an overview.非洲的移植——概述
Clin Nephrol. 2016;86 (2016)(13):90-95. doi: 10.5414/CNP86S125.
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Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy: A Preliminary Examination.认知储备作为慢性创伤性脑病临床症状的调节因素:一项初步研究
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