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左旋四咪唑联合利福平治疗瘤型麻风患者的疗效。瘤型麻风患者中的左旋四咪唑

[Effect of L-tetramisol associated with rifampicin in patients with lepromatous leprosy. L-tetramisol in patients with lepromatous leprosy].

作者信息

Galmarini M, Riera C M, Ripoll J, Orozco M A, Katz J

出版信息

Med Cutan Ibero Lat Am. 1978;6(3-4):179-83.

PMID:398916
Abstract

In this work are presented results obtained in the treament of thirty patients suffering of lepromatous leprosy. In a group of fifteen patients L-tetramisol was administrated in association to antimocrobian drugs. The control group received only the last medication. Immunological modifications were not observed in any case. However, in six patients treated with L-tetramisol associated to rifampicin during three months it was possible to observe a notable improvement of the clinical state. In the patients that received L-tetramisol associated to other drugs or in those that received only antimicrobian drugs the clinical improvement was very low or null.

摘要

本文展示了对30例瘤型麻风病患者治疗所取得的结果。在一组15例患者中,L - 四咪唑与抗菌药物联合使用。对照组仅接受后一种药物。在任何情况下均未观察到免疫改变。然而,在6例接受L - 四咪唑与利福平联合治疗3个月的患者中,观察到临床状态有显著改善。在接受L - 四咪唑与其他药物联合治疗的患者或仅接受抗菌药物治疗的患者中,临床改善非常低或没有改善。

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