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机器人辅助与传统腹腔镜子宫切除术治疗子宫内膜癌:在法国一家三级教学医院学习曲线初期的一项观察性研究。

Robot-assisted versus conventional laparoscopic hysterectomy in endometrial cancer: An observational study in a French tertiary teaching hospital at the beginning of the learning curve.

作者信息

Bajeux Emma, Hamonic Stéphanie, Brunet-Houdard Solène, Nyangoh Timoh Krystel, Dion Ludivine, Guecheff Alexia, Lavoue Vincent

机构信息

Univ Rennes, CHU Rennes, CIC 1414, Service d'Epidémiologie et de Santé publique, Hôpital Pontchaillou, 2 rue Henri Le Guilloux, F-35033 RENNES Cedex, France.

CHU Rennes, Service d'Epidémiologie et de Santé publique, Hôpital Pontchaillou, 2 rue Henri Le Guilloux, F-35033 RENNES Cedex, France.

出版信息

J Gynecol Obstet Hum Reprod. 2025 Apr;54(4):102917. doi: 10.1016/j.jogoh.2025.102917. Epub 2025 Jan 30.

Abstract

INTRODUCTION

The role of Robotic Assisted Laparoscopy (RAL) versus conventional laparoscopy (CL) in the surgical treatment of endometrial cancer remains a matter of debate. We aimed to compare RAL and CL in terms of clinical outcomes (hospital stay characteristics and 3-month complications) in patients undergoing hysterectomy for endometrial cancer.

MATERIALS AND METHODS

We conducted a single-center, retrospective study in a tertiary teaching hospital comparing two groups of women who underwent hysterectomy for endometrial carcinoma by RAL performed by a surgeon during the beginning of learning curve, or CL.

RESULTS

Of the 110 patients included, 56 were in the RAL group and 54 in the CL group. The patients in the RAL group were significantly older (71.6±8.7 vs 67.8±9.7, p=0.031) and had a higher BMI (33.1±7.0 vs 29.8±6.1, p=0.030) than those in the CL group. Operating room occupancy time was higher with RAL (4.6 hours±1.3 vs 3.5±1.3, p<0.001). Although less spinal analgesia was used in the RAL group (35% vs 74%, p<0.001), the patients in this group consumed less postoperative paracetamol (9.4g±5.3 vs 13.0±9.9, p=0.032) meaning faster recovery. Conversely, there was a higher rate of unplanned consultations during the 3-month follow-up in the RAL vs CL group (18.5% vs 3.6%, p=0.012).

DISCUSSION

RAL was associated with less postoperative pain even at the beginning of learning curve. Surgeons were more likely to perform RAL than CL for older and/or obese patients, suggesting they intuitively consider RAL of added benefit for these patients.

摘要

引言

机器人辅助腹腔镜手术(RAL)与传统腹腔镜手术(CL)在子宫内膜癌手术治疗中的作用仍存在争议。我们旨在比较接受子宫内膜癌子宫切除术患者的临床结局(住院时间特征和3个月并发症)方面的RAL和CL。

材料与方法

我们在一家三级教学医院进行了一项单中心回顾性研究,比较两组因子宫内膜癌接受子宫切除术的女性,一组是在学习曲线初期由外科医生进行的RAL手术,另一组是CL手术。

结果

纳入的110例患者中,RAL组56例,CL组54例。RAL组患者比CL组患者年龄显著更大(71.6±8.7岁对67.8±9.7岁,p = 0.031)且BMI更高(33.1±7.0对29.8±6.1,p = 0.030)。RAL的手术室占用时间更长(4.6小时±1.3对3.5±1.3,p<0.001)。虽然RAL组使用的脊柱镇痛较少(35%对74%,p<0.001),但该组患者术后对乙酰氨基酚的消耗量较少(9.4g±5.3对13.0±9.9,p = 0.032),这意味着恢复更快。相反,RAL组与CL组相比,3个月随访期间计划外会诊率更高(18.5%对3.6%,p = 0.012)。

讨论

即使在学习曲线初期,RAL与术后疼痛减轻相关。对于年龄较大和/或肥胖患者,外科医生更倾向于进行RAL而非CL,这表明他们直观地认为RAL对这些患者有额外益处。

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