Briscoe Jessica B, Venna Alyssia, Mehta Rittal, Park In Hye, Domnina Yuliya, Greenlick-Michals Hannah, Desai Manan, Tongut Aybala, Yerebakan Can, d'Udekem Yves
Division of Cardiovascular Surgery, Children's National Hospital, Washington, DC.
Division of Cardiovascular Surgery, Children's National Hospital, Washington, DC.
Ann Thorac Surg. 2025 May;119(5):1053-1061. doi: 10.1016/j.athoracsur.2025.01.015. Epub 2025 Jan 31.
Early tracheostomy improves outcomes in the adult population, but there is little evidence of benefit in the pediatric population. We investigated hospital and late survival of tracheostomy placement in patients who also underwent congenital cardiac surgery.
A single-center review of 65 consecutive patients who underwent tracheostomy placement and cardiac surgery in a pediatric hospital between 2011 and 2022 was performed. Multivariable logistic regression analysis was performed to assess predictors of mortality, and a Kaplan-Meier estimate was performed to evaluate mortality.
Final analysis included 62 patients. Median birth weight and age at tracheostomy admission was 2.7 (interquartile range [IQR], 2-3) kg and 175 (IQR, 107-266) days, respectively. Patients failed extubation a median of 3 (IQR, 1-4) times. Duration of ventilation before tracheostomy was 85 (IQR, 49-106) days. Thirty-nine patients (63%) were discharged from the hospital. Thirty-eight patients (61%) died overall, of which 21 (55%) died in hospital. Median survival was 328 (IQR, 94-1711) days. Independent predictors of mortality were longer length of stay (odds ratio [OR], 4.66; 95% CI, 1.6-13.8; P < .01), tracheomalacia (OR, 0.31; 95% CI, 0.1-0.93; P = .04), sepsis (OR 3.4; 95% CI, 1.18-10; P = .02), pneumonia before or after tracheostomy (OR, 3.3; 95% CI, 1.1-10.2; P = .04), and acute kidney injury requiring dialysis (OR, 8; 95% CI, 1.96-54.5; P = .01).
With 61% mortality after tracheostomy in patients undergoing cardiac surgery in a pediatric hospital, one can wonder whether this practice improves survival in these patients. Families should be warned that, in the sickest patients, tracheostomy may only offer increased survival for a limited time.
早期气管切开术可改善成人患者的预后,但在儿科患者中几乎没有获益的证据。我们调查了同时接受先天性心脏手术的患者气管切开术后的院内生存率和远期生存率。
对2011年至2022年期间在一家儿科医院连续接受气管切开术和心脏手术的65例患者进行单中心回顾性研究。进行多变量逻辑回归分析以评估死亡率的预测因素,并采用Kaplan-Meier估计法评估死亡率。
最终分析纳入62例患者。气管切开术入院时的出生体重中位数和年龄分别为2.7(四分位间距[IQR],2-3)kg和175(IQR,107-266)天。患者拔管失败的中位数为3(IQR,1-4)次。气管切开术前的通气时间为85(IQR,49-106)天。39例患者(63%)出院。共有38例患者(61%)死亡,其中21例(55%)死于医院。中位生存期为328(IQR,94-1711)天。死亡率的独立预测因素包括住院时间延长(比值比[OR],4.66;95%置信区间[CI],1.6-13.8;P <.01)、气管软化(OR,0.31;95% CI,0.1-0.93;P =.04)、脓毒症(OR 3.4;95% CI,1.18-10;P =.02)、气管切开术前或术后肺炎(OR,3.3;95% CI,1.1-10.2;P =.04)以及需要透析的急性肾损伤(OR,8;95% CI,1.96-54.5;P =.01)。
在一家儿科医院接受心脏手术的患者中,气管切开术后死亡率为61%,人们可能会质疑这种做法是否能提高这些患者的生存率。应告知家属,对于病情最严重的患者,气管切开术可能仅能在有限时间内提高生存率。