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用于支持治疗、感染控制和公共卫生的碳青霉烯酶机制检测:临床实验室的作用

Carbapenemase Mechanism Testing to Support Treatment, Infection Control, and Public Health: The Role of the Clinical Laboratory.

作者信息

Blosser Sara J, Bhatnagar Amelia S, Bollinger Susan, Giffen Samantha R

机构信息

Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA; Goldbelt Professional Services, LLC, Chesapeake, VA, USA.

Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

出版信息

Clin Lab Med. 2025 Mar;45(1):51-61. doi: 10.1016/j.cll.2024.10.006. Epub 2024 Nov 16.

Abstract

Carbapenemase mechanism testing in carbapenem-resistant Enterobacterales is essential for informing patient treatment, infection prevention, and control. By highlighting the clinical and infection control imperative for this testing, addressing current barriers, and delineating future needs, we set the stage and advocate for routine carbapenemase mechanism testing in all clinical laboratories in the United States.

摘要

对耐碳青霉烯类肠杆菌科细菌进行碳青霉烯酶机制检测对于指导患者治疗、预防和控制感染至关重要。通过强调该检测在临床和感染控制方面的紧迫性、解决当前存在的障碍并描述未来需求,我们奠定了基础并倡导在美国所有临床实验室开展常规碳青霉烯酶机制检测。

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Laboratory detection of carbapenemases among Gram-negative organisms.革兰氏阴性菌中碳青霉烯酶的实验室检测
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