Hurle J M, Colvee E, Fernandez-Teran M A
J Embryol Exp Morphol. 1985 Feb;85:239-50.
The pattern and structure of the blood vessels of the interdigital spaces of the leg bud have been studied by means of Indian ink injections and transmission electron microscopy in the chick and duck embryos. The results show that in the chick the interdigital necrotic process responsible for the freeing of the digits is followed by regression of the blood vessels. In the webbed foot of the duck, the interdigital necrotic processes are not followed by vascular regression. Transmission electron microscopic studies show that both in the chick and in the duck, interdigital blood vessels are immature structures lacking basal lamina. Dead cells of presumably endothelial origin were detected in the lumen of the regressing blood vessels of the chick but not in the duck. However, the intensity of this cell death process does not appear to be high enough to account by itself for the disappearance of the interdigital blood vessels. The possible relationships between interdigital mesenchymal cell death and vascular regression are discussed.
通过对鸡和鸭胚胎进行印度墨汁注射及透射电子显微镜观察，研究了腿芽指间间隙血管的模式和结构。结果表明，在鸡中，导致趾分离的指间坏死过程之后是血管的退化。在鸭的蹼足中，指间坏死过程之后并未出现血管退化。透射电子显微镜研究显示，在鸡和鸭中，指间血管都是缺乏基膜的不成熟结构。在鸡退化血管的管腔中检测到了可能源自内皮的死亡细胞，而在鸭中未检测到。然而，这种细胞死亡过程的强度似乎不足以单独解释指间血管的消失。文中还讨论了指间间充质细胞死亡与血管退化之间可能的关系。
