• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Surgical Outcomes Stratified by Type of Transportation and Presence of Coronary Reperfusion in Patients with Coronary Malperfusion Caused by Type A Aortic Dissection.

作者信息

Noda Kazuki, Inoue Yosuke, Seike Yoshimasa, Matsuda Hitoshi

机构信息

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.

出版信息

Ann Thorac Cardiovasc Surg. 2025;31(1). doi: 10.5761/atcs.oa.24-00182.

DOI:10.5761/atcs.oa.24-00182
PMID:39894562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11873597/
Abstract

PURPOSE

Owing to the time-sensitive nature of myocardial ischemia, challenging clinical scenarios should be considered in patients with type A acute aortic dissection (AAAD) complicated by coronary malperfusion. In clinical settings, the diagnosis and reperfusion strategies for coronary malperfusion often depend on institutional resources. This study evaluated early surgical outcomes in such patients, focusing on transportation type and clinical management.

METHODS

We retrospectively reviewed 70 patients who underwent emergency surgery for AAAD with coronary malperfusion, excluding those with cardiac tamponade on arrival, between 1997 and February 2024. Patients were divided into 2 groups based on transportation: direct transfer and referral.

RESULTS

Overall, in-hospital mortality was 27%, with only 1 of 9 patients surviving with preoperative peripheral extracorporeal membrane oxygenation (ECMO). Mortality and morbidity did not significantly differ between groups. Univariate analysis identified left coronary artery involvement and preoperative hemodynamic instability as significant risk factors. Additionally, preoperative diagnostic-only coronary angiography (CAG) with unsuccessful reperfusion was a potential risk factor (P = 0.06).

CONCLUSIONS

Regardless of transportation type, preoperative peripheral ECMO itself could not be a definitive solution in AAAD patients with coronary malperfusion. Also, patients who underwent preoperative CAG with unsuccessful reperfusion might be fatal, especially with suspected left coronary artery involvement.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e7/11873597/498d144e787e/atcs-31-1-24-00182-figure03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e7/11873597/bcc662e6fac0/atcs-31-1-24-00182-figure01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e7/11873597/fd3e369e9c00/atcs-31-1-24-00182-figure02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e7/11873597/498d144e787e/atcs-31-1-24-00182-figure03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e7/11873597/bcc662e6fac0/atcs-31-1-24-00182-figure01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e7/11873597/fd3e369e9c00/atcs-31-1-24-00182-figure02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e7/11873597/498d144e787e/atcs-31-1-24-00182-figure03.jpg

相似文献

1
Surgical Outcomes Stratified by Type of Transportation and Presence of Coronary Reperfusion in Patients with Coronary Malperfusion Caused by Type A Aortic Dissection.
Ann Thorac Cardiovasc Surg. 2025;31(1). doi: 10.5761/atcs.oa.24-00182.
2
Survival after operative repair of acute type A aortic dissection varies according to the presence and type of preoperative malperfusion.急性 A 型主动脉夹层手术后的存活率因术前存在的和类型的灌注不良而异。
J Thorac Cardiovasc Surg. 2024 Jul;168(1):37-49.e6. doi: 10.1016/j.jtcvs.2022.09.034. Epub 2022 Sep 29.
3
Abrupt left coronary artery malperfusion secondary to acute type A aortic dissection after weaning from cardiopulmonary bypass: a case report.体外循环撤机后急性A型主动脉夹层继发左冠状动脉急性灌注不良:一例报告
BMC Cardiovasc Disord. 2025 Mar 7;25(1):161. doi: 10.1186/s12872-025-04556-4.
4
Treatment of coronary malperfusion in type A acute aortic dissection.A型急性主动脉夹层中冠状动脉灌注不良的治疗。
Gen Thorac Cardiovasc Surg. 2018 Nov;66(11):621-625. doi: 10.1007/s11748-018-1014-y. Epub 2018 Sep 14.
5
Clinical presentation, management, and short-term outcome of patients with type A acute dissection complicated by mesenteric malperfusion: observations from the International Registry of Acute Aortic Dissection.急性 A 型主动脉夹层合并肠系膜动脉灌注不良患者的临床表现、处理和短期转归:国际急性主动脉夹层注册研究的观察结果。
J Thorac Cardiovasc Surg. 2013 Feb;145(2):385-390.e1. doi: 10.1016/j.jtcvs.2012.01.042. Epub 2012 Feb 15.
6
Malperfusion in type A aortic dissection: results of emergency central aortic repair.A型主动脉夹层的灌注不良:急诊主动脉中央修复的结果
Gen Thorac Cardiovasc Surg. 2019 Jul;67(7):594-601. doi: 10.1007/s11748-019-01072-z. Epub 2019 Feb 7.
7
Managing patients with acute type A aortic dissection and mesenteric malperfusion syndrome: A 20-year experience.管理急性 A 型主动脉夹层合并肠系膜动脉灌注不良综合征患者:20 年经验。
J Thorac Cardiovasc Surg. 2019 Sep;158(3):675-687.e4. doi: 10.1016/j.jtcvs.2018.11.127. Epub 2018 Dec 14.
8
Immediate operation for acute type A aortic dissection complicated by visceral or peripheral malperfusion.急性 A 型主动脉夹层合并内脏或外周血运障碍的即刻手术治疗。
J Thorac Cardiovasc Surg. 2018 Jul;156(1):18-24.e3. doi: 10.1016/j.jtcvs.2018.01.096. Epub 2018 Feb 21.
9
Percutaneous coronary intervention for left main coronary artery malperfusion in acute type A aortic dissection.经皮冠状动脉介入治疗急性 A 型主动脉夹层左主干冠状动脉灌注不良。
Cardiovasc Interv Ther. 2022 Apr;37(2):333-342. doi: 10.1007/s12928-021-00793-4. Epub 2021 Jul 13.
10
Two surgical strategies (early carotid reperfusion vs. Central aortic repair-first) of acute type a aortic dissection complicated with cerebral malperfusion syndrome: a meta-analysis and systematic review.两种手术策略(早期颈动脉再灌注与主动脉根部修复优先)治疗合并脑灌注不良综合征的急性 A 型主动脉夹层:一项荟萃分析和系统评价。
BMC Cardiovasc Disord. 2024 May 7;24(1):239. doi: 10.1186/s12872-024-03910-2.

本文引用的文献

1
Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock.微轴流泵与常规治疗在梗死相关性心源性休克中的比较。
N Engl J Med. 2024 Apr 18;390(15):1382-1393. doi: 10.1056/NEJMoa2312572. Epub 2024 Apr 7.
2
Outcomes of type A acute aortic dissection with cardiopulmonary arrest: Tokyo Acute Aortic Super-network Registry.伴有心肺骤停的A型急性主动脉夹层的预后:东京急性主动脉超级网络注册研究
Eur J Cardiothorac Surg. 2023 Apr 3;63(4). doi: 10.1093/ejcts/ezad056.
3
Treatment strategies and in-hospital mortality in patients with type A acute aortic dissection and coronary artery involvement.
A型急性主动脉夹层合并冠状动脉受累患者的治疗策略和院内死亡率。
J Thorac Cardiovasc Surg. 2024 Feb;167(2):596-601.e3. doi: 10.1016/j.jtcvs.2022.03.016. Epub 2022 Mar 29.
4
Percutaneous coronary intervention for left main coronary artery malperfusion in acute type A aortic dissection.经皮冠状动脉介入治疗急性 A 型主动脉夹层左主干冠状动脉灌注不良。
Cardiovasc Interv Ther. 2022 Apr;37(2):333-342. doi: 10.1007/s12928-021-00793-4. Epub 2021 Jul 13.
5
2021 The American Association for Thoracic Surgery expert consensus document: Surgical treatment of acute type A aortic dissection.2021年美国胸外科医师协会专家共识文件:急性A型主动脉夹层的外科治疗
J Thorac Cardiovasc Surg. 2021 Sep;162(3):735-758.e2. doi: 10.1016/j.jtcvs.2021.04.053. Epub 2021 Apr 30.
6
Analysis of Acute Type A Aortic Dissection in Japan Registry of Aortic Dissection (JRAD).日本胸主动脉夹层注册研究(JRAD)中急性 A 型主动脉夹层分析。
Ann Thorac Surg. 2020 Sep;110(3):790-798. doi: 10.1016/j.athoracsur.2019.12.051. Epub 2020 Feb 6.
7
Early reperfusion strategy improves the outcomes of surgery for type A acute aortic dissection with malperfusion.早期再灌注策略可改善合并灌注不良的急性 A 型主动脉夹层手术的结局。
J Thorac Cardiovasc Surg. 2018 Aug;156(2):483-489. doi: 10.1016/j.jtcvs.2018.02.007. Epub 2018 Feb 13.
8
Risk analysis and improvement of strategies in patients who have acute type A aortic dissection with coronary artery dissection.急性 A 型主动脉夹层合并冠状动脉夹层患者的风险分析及策略改善。
Eur J Cardiothorac Surg. 2013 Sep;44(3):419-24; discussion 424-5. doi: 10.1093/ejcts/ezt060. Epub 2013 Mar 15.
9
Third universal definition of myocardial infarction.心肌梗死的第三次全球定义。
Circulation. 2012 Oct 16;126(16):2020-35. doi: 10.1161/CIR.0b013e31826e1058. Epub 2012 Aug 24.
10
Should we emergently revascularize occluded coronaries for cardiac arrest?: rapid-response extracorporeal membrane oxygenation and intra-arrest percutaneous coronary intervention.对于心搏骤停患者,我们是否应该立即对闭塞的冠状动脉进行血运重建?:快速反应体外膜肺氧合和心搏骤停时经皮冠状动脉介入治疗。
Circulation. 2012 Sep 25;126(13):1605-13. doi: 10.1161/CIRCULATIONAHA.111.067538. Epub 2012 Aug 16.