Park Enoch, Peterson Lindsay, McKeon Shawn, Fiala Mark A
School of Medicine, Saint Louis University, 1402 S Grand Blvd, St Louis, MO, 63104, USA.
Division of Oncology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus, Box 8056, St Louis, MO, 63110, USA.
Breast Cancer Res Treat. 2025 May;211(1):91-97. doi: 10.1007/s10549-025-07624-7. Epub 2025 Feb 2.
This study explored changes in employment and financial hardship following breast cancer diagnosis.
We used data from a single-institution, longitudinal study of women with newly diagnosed breast cancer who received curative intent chemotherapy. The primary outcomes of interest in this analysis were breaks in active employment, defined as being out of work for the four weeks prior, and patient-reported acute financial burden during chemotherapy and up to 24 months following chemotherapy completion. Mixed-effects logistic regression models were used to identify factors associated with breaks in employment and financial burden.
The cohort consisted of 104 women who were employed at time of breast cancer diagnosis. The mean age was 49.6 years and 86% were non-Hispanic White, 11% African American or Black, and 4% another race or ethnicity. In multivariable models, African-American women were 168% more likely to report a break from active employment than their non-Hispanic white counterparts (adjusted odds ration [aOR] 2.68; p = 0.026). A break from active employment was not statistically associated with greater self-reported acute financial burden, but patients from the lowest socioeconomic status tertile were 173% more likely to report financial burden than those in the highest tertile (aOR 2.73; p = 0.022).
African-American breast cancer survivors were more likely to report breaks from active employment than their White peers, even after adjusting for type of work and socioeconomic status.
African-American and Black breast cancer survivors may face greater challenges returning to work.
本研究探讨乳腺癌诊断后就业情况和经济困难的变化。
我们使用了来自一项单机构纵向研究的数据，该研究针对接受根治性化疗的新诊断乳腺癌女性。本分析中感兴趣的主要结局是在职工作中断，定义为前四周失业，以及患者报告的化疗期间及化疗结束后长达24个月的急性经济负担。使用混合效应逻辑回归模型来确定与就业中断和经济负担相关的因素。
该队列由104名在乳腺癌诊断时就业的女性组成。平均年龄为49.6岁，86%为非西班牙裔白人，11%为非裔美国人或黑人，4%为其他种族或族裔。在多变量模型中，非裔美国女性报告在职工作中断的可能性比非西班牙裔白人女性高168%（调整后的优势比[aOR]为2.68；p = 0.026）。在职工作中断与更高的自我报告急性经济负担无统计学关联，但社会经济地位最低三分位数组的患者报告经济负担的可能性比最高三分位数组高173%（aOR为2.73；p = 0.022）。
即使在调整工作类型和社会经济地位后，非裔美国乳腺癌幸存者比白人同龄人更有可能报告在职工作中断。
非裔美国和黑人乳腺癌幸存者在重返工作岗位时可能面临更大挑战。
