Berger S J, Carter J G, Lowry O H
J Neurochem. 1985 Jun;44(6):1736-40. doi: 10.1111/j.1471-4159.1985.tb07162.x.
Guanine deaminase was measured in nearly 100 different areas of mouse brain. The levels are relatively high in all parts of the telencephalon, both gray and white. It is especially active in parts of the olfactory tubercle and amygdala. Levels in the diencephalon range from low to as high as in the telencephalon. Brain areas caudal to the diencephalon, including all parts of the cerebellum, are almost uniformly below the level of detection. The enzyme is also virtually absent from the retina. The extreme range of concentration suggests that guanine deaminase might play a role in the metabolism of a neuroeffector.
在小鼠大脑近100个不同区域测量了鸟嘌呤脱氨酶。端脑的所有部分,无论是灰质还是白质,该酶水平都相对较高。它在嗅结节和杏仁核的部分区域特别活跃。间脑的水平从低到与端脑一样高。间脑尾部的脑区,包括小脑的所有部分,几乎都低于检测水平。视网膜中实际上也没有这种酶。浓度的极大差异表明鸟嘌呤脱氨酶可能在神经效应器的代谢中起作用。