A Case Report of Anti-GD3 Antibody Positive Incomplete Miller-Fisher Syndrome With Pyramidal Tract Symptoms.

Incomplete Miller-Fisher syndrome (MFS) is a rare autoimmune disorder affecting the nervous system. In contrast to classical MFS, its clinical manifestations are often atypical and may be characterized by the absence of certain features, such as extraocular muscle paralysis and the loss of tendon reflexes. The presence of anti-GD3 antibodies is infrequently observed in these patients. This case report describes a patient diagnosed with incomplete MFS who exhibited positive anti-GD3 antibody results and presented with pyramidal tract signs. This suggests that anti-GD3 antibodies may play a role in the pathogenesis of some atypical forms of MFS, warranting attention in clinical practice.