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空肠恶性血管球瘤伴肝及腹膜转移:一例罕见病例报告

Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report.

作者信息

Peng Shilan, Yang Nan, Xu Zifan, Su Guomiao, Tuo Xiaoyu, Liu Shiyue, Lei Zi, Pan Guoqing

机构信息

Department of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, China.

College of The First Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, China.

出版信息

Front Oncol. 2025 Jan 17;14:1519968. doi: 10.3389/fonc.2024.1519968. eCollection 2024.

Abstract

Glomus tumors (GTs) are rare mesenchymal neoplasms that occur predominantly on the subungual region of the distal extremities and are rarely seen in visceral organs such as the gastrointestinal tract. Malignant glomus tumors (MGTs) is even more rare, comprising less than 1% of all GTs. We reported an 82-year-old female patient with MGTs of the jejunum, accompanied by metastases to the liver and peritoneum. The patient presented with a primary complaint of epigastric pain with nausea and acid reflux for two months. Computed tomography scan revealed a prominently enhanced, inhomogeneous-density mass in the jejunum, the nature of which-benign or malignant-could not initially be determined. Postoperative pathological diagnosis confirmed the lesion to be a jejunal MGT. Regrettably, the patient declined additional treatment, subsequently developing liver and peritoneal metastases one year later. She eventually died within 18 months of initial diagnosis. This report summarizes the clinical and histopathological features of jejunal MGTs with the aim of increasing awareness among clinicians and pathologists regarding this disease.

摘要

血管球瘤(GTs)是一种罕见的间叶组织肿瘤,主要发生在远端肢体的甲下区域,很少见于胃肠道等内脏器官。恶性血管球瘤(MGTs)更为罕见,占所有GTs的比例不到1%。我们报告了一名82岁的女性患者,患有空肠MGTs,并伴有肝转移和腹膜转移。患者的主要诉求是上腹部疼痛伴恶心和反酸两个月。计算机断层扫描显示空肠有一个明显强化、密度不均匀的肿块,最初无法确定其性质是良性还是恶性。术后病理诊断证实病变为空肠MGT。遗憾的是,患者拒绝进一步治疗,随后在一年后出现肝转移和腹膜转移。她最终在初次诊断后的18个月内死亡。本报告总结了空肠MGTs的临床和组织病理学特征,旨在提高临床医生和病理学家对该疾病的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ca/11782956/488481c8987f/fonc-14-1519968-g001.jpg

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