Inoue Yuzaburo, Ogata Hitoshi, Sato Yoshitake, Kato Daigo, Mitsunaga Kanako, Saito Mamiko, Ishigaki Tatsuya, Tomiita Minako, Kuraishi Hiroshi, Ito Keisuke, Ueki Shigeharu
Department of General Medical Science, Graduate School of Medicine, Chiba University, Chiba, Japan.
Department of Allergy and Rheumatology, Chiba Children's Hospital, Chiba, Japan.
J Allergy Clin Immunol Glob. 2024 Dec 25;4(2):100397. doi: 10.1016/j.jacig.2024.100397. eCollection 2025 May.
Two cases of refractory Kimura disease that required treatment with biologic agents are reported. Their pathology suggests the involvement of eosinophil ETosis, which is active cell death producing Charcot-Leyden crystals.
报告了两例需要使用生物制剂治疗的难治性木村病病例。其病理显示嗜酸性粒细胞胞吐作用参与其中,这是一种产生夏科-莱登结晶的活性细胞死亡过程。