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Roflumilast in Dermatology: A Newer Phosphodiesterase-4 Inhibitor.

作者信息

Singh Suvesh, Paul Debopriya, Snehal Aditi

机构信息

From the Department of Dermatology, AIIMS, Patna, Bihar, India E-mail:

出版信息

Indian J Dermatol. 2025 Jan-Feb;70(1):38-41. doi: 10.4103/ijd.ijd_261_24. Epub 2024 Dec 30.

DOI:10.4103/ijd.ijd_261_24
PMID:39896310
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11784981/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c8/11784981/395c51a4d80d/IJD-70-38-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c8/11784981/395c51a4d80d/IJD-70-38-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c8/11784981/395c51a4d80d/IJD-70-38-g001.jpg

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Roflumilast in Dermatology: A Newer Phosphodiesterase-4 Inhibitor.罗氟司特在皮肤科的应用:一种新型磷酸二酯酶-4抑制剂
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2
[Translated aticle] Topical and Oral Roflumilast in Dermatology: A Narrative Review.[翻译文章] 皮肤病学中局部和口服罗氟司特:一篇叙述性综述。
Actas Dermosifiliogr. 2024 Mar;115(3):T265-T279. doi: 10.1016/j.ad.2024.01.009. Epub 2024 Jan 13.
3
Roflumilast: first phosphodiesterase 4 inhibitor approved for treatment of COPD.罗氟司特:首个获批用于治疗慢性阻塞性肺疾病的磷酸二酯酶4抑制剂。
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The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease.罗氟司特的临床前药理学——一种用于慢性阻塞性肺疾病的选择性、口服磷酸二酯酶 4 抑制剂。
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Phosphodiesterase 4 Inhibitor Roflumilast Protects Rat Hippocampal Neurons from Sevoflurane Induced Injury via Modulation of MEK/ERK Signaling Pathway.磷酸二酯酶4抑制剂罗氟司特通过调节MEK/ERK信号通路保护大鼠海马神经元免受七氟醚诱导的损伤。
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Effects of roflumilast, a phosphodiesterase-4 inhibitor, on hypoxia- and monocrotaline-induced pulmonary hypertension in rats.磷酸二酯酶-4抑制剂罗氟司特对大鼠缺氧和野百合碱诱导的肺动脉高压的影响。
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本文引用的文献

1
Phosphodiesterase-4 Inhibition in the Management of Psoriasis.磷酸二酯酶-4抑制剂在银屑病治疗中的应用
Pharmaceutics. 2023 Dec 22;16(1):23. doi: 10.3390/pharmaceutics16010023.
2
Roflumilast foam 0.3% for adolescent and adult patients with seborrheic dermatitis: A randomized, double-blinded, vehicle-controlled, phase 3 trial.罗氟司特泡沫 0.3%治疗青少年和成年脂溢性皮炎患者的随机、双盲、赋形剂对照、3 期临床试验。
J Am Acad Dermatol. 2024 May;90(5):986-993. doi: 10.1016/j.jaad.2023.12.065. Epub 2024 Jan 20.
3
[Translated aticle] Topical and Oral Roflumilast in Dermatology: A Narrative Review.
[翻译文章] 皮肤病学中局部和口服罗氟司特:一篇叙述性综述。
Actas Dermosifiliogr. 2024 Mar;115(3):T265-T279. doi: 10.1016/j.ad.2024.01.009. Epub 2024 Jan 13.
4
ZORYVE (Roflumilast) Cream: A Topical Phosphodiesterase-4 Inhibitor for the Treatment of Psoriasis.佐立维(罗氟司特)乳膏:一种用于治疗银屑病的外用磷酸二酯酶-4抑制剂。
Skinmed. 2023 Nov 10;21(5):357-359. eCollection 2023.
5
Topical Roflumilast for Plaque Psoriasis.局部用罗氟司特治疗斑块状银屑病。
Skin Therapy Lett. 2023 Sep;28(5):1-4.
6
Topical and Oral Roflumilast in Dermatology: A Narrative Review.局部用和口服罗氟司特在皮肤科的应用:综述。
7
Efficacy and safety of oral roflumilast for moderate-to-severe psoriasis-a randomized controlled trial (PSORRO).口服罗氟司特治疗中重度银屑病的疗效和安全性——一项随机对照试验(PSORRO)
Lancet Reg Health Eur. 2023 Apr 21;30:100639. doi: 10.1016/j.lanepe.2023.100639. eCollection 2023 Jul.
8
Topical roflumilast for the treatment of psoriasis.外用罗氟司特治疗银屑病。
Expert Rev Clin Immunol. 2023 Jul-Dec;19(9):1053-1062. doi: 10.1080/1744666X.2023.2219897. Epub 2023 May 30.
9
Refractory Behçet disease succesfully treated with roflumilast.用罗氟司特成功治疗难治性白塞病。
Clin Exp Dermatol. 2023 Aug 25;48(9):1060-1062. doi: 10.1093/ced/llad189.
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JAMA Dermatol. 2023 Jun 1;159(6):613-620. doi: 10.1001/jamadermatol.2023.0846.