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青少年重度抑郁症患者的混合式电休克治疗:一例报告

Hybrid electroconvulsive therapy in an adolescent with major depressive disorder: a case report.

作者信息

Zhang Jing-Ya, Li Jia, Wang Nan, Xie Xin-Hui, Zeng Lun

机构信息

Department of Clinical Psychology, The Second People's Hospital of Huizhou, Huizhou, Guangdong, China.

Electroconvulsive Therapy Room, Department of Psychosomatic Medicine, The Second People's Hospital of Huizhou, Huizhou, Guangdong, China.

出版信息

Front Psychiatry. 2025 Jan 17;15:1487983. doi: 10.3389/fpsyt.2024.1487983. eCollection 2024.

DOI:10.3389/fpsyt.2024.1487983
PMID:39896996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11783184/
Abstract

The incidence of depression is increasing in adolescents, who are at a stage of education and therefore more concerned about their cognitive changes. We tried to preserve the rapid relief of depressive symptoms in electroconvulsive therapy (ECT) while causing less cognitive impairment, thus designing the hybrid-ECT (HECT), a modified ECT therapy. Here, we report a case study of a 14-year-old male student with major depressive disorder (MDD) suffering from severe suicidality and significant impairment in social functioning who achieved effective antidepressant effects with HECT and improved cognitive function. HECT showed safety and effectiveness in adolescent MDD patient.

摘要

青少年抑郁症的发病率正在上升,他们正处于受教育阶段,因此更关注自己的认知变化。我们试图在电休克治疗(ECT)中保持对抑郁症状的快速缓解,同时减少认知损害,从而设计了混合式电休克治疗(HECT),这是一种改良的ECT治疗方法。在此,我们报告一例14岁男性重度抑郁症(MDD)学生的病例研究,该患者有严重自杀倾向且社会功能严重受损,接受HECT治疗后获得了有效的抗抑郁效果且认知功能得到改善。HECT在青少年MDD患者中显示出安全性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f47c/11783184/4fc42509a2c5/fpsyt-15-1487983-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f47c/11783184/4fc42509a2c5/fpsyt-15-1487983-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f47c/11783184/4fc42509a2c5/fpsyt-15-1487983-g001.jpg

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本文引用的文献

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Factors associated with early and late response to electroconvulsive therapy.与电抽搐治疗的早期和晚期反应相关的因素。
Acta Psychiatr Scand. 2023 Apr;147(4):322-332. doi: 10.1111/acps.13537. Epub 2023 Feb 20.
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Trajectories of Efficacy and Cognitive Function During Electroconvulsive Therapy Course in Young Adults with Treatment-Resistant Depression.难治性抑郁症青年患者电休克治疗过程中的疗效及认知功能轨迹
Neuropsychiatr Dis Treat. 2023 Jan 29;19:267-281. doi: 10.2147/NDT.S394155. eCollection 2023.
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A retrospective case series of electroconvulsive therapy in the management of depression and suicidal symptoms in adolescents.
一项回顾性病例系列研究,探讨电抽搐治疗在青少年抑郁症和自杀症状管理中的应用。
Brain Behav. 2022 Nov;12(11):e2795. doi: 10.1002/brb3.2795. Epub 2022 Oct 19.
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Improved Safety of Hybrid Electroconvulsive Therapy Compared With Standard Electroconvulsive Therapy in Patients With Major Depressive Disorder: A Randomized, Double-Blind, Parallel-Group Pilot Trial.与标准电休克治疗相比,改良式电休克治疗对重度抑郁症患者安全性的改善:一项随机、双盲、平行组的试点试验。
Front Psychiatry. 2022 May 23;13:896018. doi: 10.3389/fpsyt.2022.896018. eCollection 2022.
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Electroconvulsive Therapy in Children and Adolescents: A Systematic Review of Current Literature and Guidelines.儿童和青少年电抽搐治疗:当前文献和指南的系统评价。
J ECT. 2021 Sep 1;37(3):158-170. doi: 10.1097/YCT.0000000000000761.
7
A 20 Year Practice Review of Electroconvulsive Therapy for Adolescents.青少年电休克治疗20年实践回顾
J Child Adolesc Psychopharmacol. 2016 Sep;26(7):632-6. doi: 10.1089/cap.2015.0139. Epub 2016 Jan 19.
8
Bifrontal, bitemporal and right unilateral electrode placement in ECT: randomised trial.额颞双侧和右侧单侧电极放置在电抽搐治疗中的随机试验。
Br J Psychiatry. 2010 Mar;196(3):226-34. doi: 10.1192/bjp.bp.109.066183.