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辐射诱导龋:探寻应对挑战的途径

Radiation-Induced Caries: Exploring the Pathway to Manage the Challenge.

作者信息

El Harram Sara, Sqalli Tarik

机构信息

Department of Dental Sciences, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University in Fes, Fes, MAR.

Laboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University in Fes, Fes, MAR.

出版信息

Cureus. 2025 Jan 2;17(1):e76810. doi: 10.7759/cureus.76810. eCollection 2025 Jan.

DOI:10.7759/cureus.76810
PMID:39897270
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11787047/
Abstract

Radiation-induced caries represent a frequent and serious complication of head and neck radiotherapy, significantly affecting patients' quality of life. Their development results from several factors, including the direct effects of radiotherapy on dental tissues, as well as indirect effects related to xerostomia and changes in saliva. Diagnosis is based on clinical and radiographic assessment, which often reveals a specific pattern of demineralization. The management of these caries requires a comprehensive approach, combining prevention, treatment of lesions, and regular follow-up. It is essential to establish long-term fluoride prophylaxis, and advice on oral hygiene and nutrition, in order to prevent new lesions. The choice of dental restorations must be considered according to the state of salivation and the caries risk, favoring materials adapted to the specificities of radiotherapy.

摘要

放射性龋齿是头颈部放疗常见且严重的并发症,显著影响患者生活质量。其发生由多种因素导致,包括放疗对牙齿组织的直接影响,以及与口干症和唾液变化相关的间接影响。诊断基于临床和影像学评估,通常会发现特定的脱矿模式。这些龋齿的管理需要综合方法,包括预防、病变治疗和定期随访。建立长期氟化物预防措施以及提供口腔卫生和营养方面的建议以预防新病变至关重要。必须根据唾液分泌状态和龋齿风险来考虑牙科修复体的选择,优先选用适合放疗特殊性的材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fed/11787047/ba05703b06fb/cureus-0017-00000076810-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fed/11787047/b36aad986190/cureus-0017-00000076810-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fed/11787047/4a3a7c9294d8/cureus-0017-00000076810-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fed/11787047/ba05703b06fb/cureus-0017-00000076810-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fed/11787047/b36aad986190/cureus-0017-00000076810-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fed/11787047/4a3a7c9294d8/cureus-0017-00000076810-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fed/11787047/ba05703b06fb/cureus-0017-00000076810-i03.jpg

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Radiation-Induced Caries: Exploring the Pathway to Manage the Challenge.辐射诱导龋:探寻应对挑战的途径
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本文引用的文献

1
Radiation-induced xerostomia and cariogenic dietary habits.辐射性口干症和致龋饮食习惯。
Support Care Cancer. 2024 Jan 9;32(2):92. doi: 10.1007/s00520-023-08298-x.
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Management of Oral Hygiene in Head-Neck Cancer Patients Undergoing Oncological Surgery and Radiotherapy: A Systematic Review.头颈癌患者接受肿瘤外科手术和放疗时的口腔卫生管理:一项系统评价
Dent J (Basel). 2023 Mar 16;11(3):83. doi: 10.3390/dj11030083.
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The Effects of Radiotherapy on Microhardness and Mineral Composition of Tooth Structures.放射治疗对牙齿结构显微硬度和矿物质成分的影响。
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Oral Oncol. 2022 Jun;129:105869. doi: 10.1016/j.oraloncology.2022.105869. Epub 2022 Apr 26.
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Head and neck radiotherapy effects on the dental pulp vitality and response to sensitivity tests: A systematic review with meta-analysis.头颈部放疗对牙髓活力及对敏感度测试反应的影响:系统评价与荟萃分析。
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Intraoral radiation stents-Primer for clinical use in head and neck cancer therapy.口腔内放射支架——头颈部癌症治疗中临床应用的基础。
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Conformational and constitutional analysis of dental caries following radiotherapy for head and neck cancer.头颈部癌放疗后龋齿的构象和结构分析
Rep Pract Oncol Radiother. 2021 Jun 9;26(3):389-399. doi: 10.5603/RPOR.a2021.0046. eCollection 2021.
8
The effect of comprehensive oral care program on oral health and quality of life in patients undergoing radiotherapy for head and neck cancer: A quasi-experimental case-control study.综合口腔护理方案对头颈部癌症放疗患者口腔健康和生活质量的影响:一项准实验性病例对照研究。
Medicine (Baltimore). 2021 Apr 23;100(16):e25540. doi: 10.1097/MD.0000000000025540.
9
Impact of head and neck radiotherapy on the longevity of dental adhesive restorations: A systematic review and meta-analysis.头颈部放疗对牙用黏接修复体寿命的影响:系统评价和荟萃分析。
J Prosthet Dent. 2022 Nov;128(5):886-896. doi: 10.1016/j.prosdent.2021.02.002. Epub 2021 Mar 11.
10
Is there evidence that radiotherapy for head and neck cancer influences the incidence of dental caries?有没有证据表明头颈部癌症的放射治疗会影响龋齿的发病率?
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