Zabbo A, Montie J E, Orlowski J P
J Urol. 1985 May;133(5):789-91. doi: 10.1016/s0022-5347(17)49229-9.
Perioperative plasma antidiuretic hormone (vasopressin) levels were determined in 8 patients undergoing radical cystectomy. Marked elevations of antidiuretic hormone were noted immediately postoperatively in all patients and these levels persisted for 48 hours. Plasma antidiuretic hormone was elevated beyond the physiological levels needed for maintenance of intravascular volume and osmolarity. Excessive antidiuretic hormone secretion is common after radical cystectomy and should be considered in the differential diagnosis of postoperative oliguria in these patients.
对8例行根治性膀胱切除术的患者测定了围手术期血浆抗利尿激素(血管加压素)水平。所有患者术后即刻均出现抗利尿激素显著升高,且这些水平持续了48小时。血浆抗利尿激素升高超过了维持血管内容量和渗透压所需的生理水平。根治性膀胱切除术后抗利尿激素分泌过多很常见,在这些患者术后少尿的鉴别诊断中应予以考虑。