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青少年牙列拥挤固定矫治非拔牙治疗中根尖外吸收的评估及中间段影像学检查的相关性:一项使用锥形束计算机断层扫描的多中心随机对照试验

Evaluation of External Apical Root Resorption and the Relevance of Intermediate Radiography in Non-Extraction Treatment With Fixed Appliances for Adolescents With Crowding: A Multicenter Randomised Controlled Trial Using CBCT.

作者信息

Johansson Kristina, Christell Helena, Brechter Anna, Paulsson Liselotte

机构信息

Faculty of Odontology, Malmö University, Malmö, Sweden.

Department of Orthodontics, Östersund Hospital, Östersund, Sweden.

出版信息

Orthod Craniofac Res. 2025 Jun;28(3):515-526. doi: 10.1111/ocr.12903. Epub 2025 Feb 3.

Abstract

OBJECTIVES

The objectives are to assess the severity and frequency of clinically relevant external apical root resorption (EARR) ≥ 2 mm during orthodontic treatment with Damon passive self-ligating and Victory conventional standardised fixed appliance systems and to evaluate the relevance of intermediate radiographic examinations for early detection and prevention of severe EARR.

MATERIALS AND METHODS

Adolescents aged 12-17 years with crowded and displaced teeth planned for non-extraction treatment were recruited from three orthodontic clinics. Participants were randomly allocated in a 1:1 ratio to treatment with either Damon Q (n = 35) or Victory (n = 40) using stratified blocks, with allocation concealed. EARR was assessed for all roots from incisors to molars using multiplanar reconstruction in cone beam computed tomography (CBCT) images acquired from various CBCT machines before, during and after treatment.

RESULTS

Sixty-two patients were included in the EARR analysis. The upper incisors were the most affected tooth group, with mean EARR values of 0.20 mm for Damon and 0.51 mm for Victory (NS, alpha 1%). The frequency of clinically relevant EARR in this tooth group was 5.0% for Damon and 7.2% for Victory (NS, alpha 5%). Only one case with clinically relevant EARR after treatment was identified in the intermediate radiographic examinations.

CONCLUSIONS

The overall severity and frequency of EARR were below clinically relevant levels in both treatment groups. The results strengthen the evidence that routine intermediate radiography appears to be of limited relevance for early detection and prevention of severe EARR in non-extraction treatments for adolescents with crowded teeth.

TRIAL REGISTRATION

ClinicalTrials.gov: NCT05664282.

摘要

目的

本研究旨在评估使用Damon被动自结扎矫治系统和Victory传统标准化固定矫治系统进行正畸治疗期间,临床相关的根尖外吸收(EARR)≥2mm的严重程度和发生率,并评估中期影像学检查对EARR早期检测和预防的相关性。

材料与方法

从三家正畸诊所招募12至17岁计划进行非拔牙矫治的牙列拥挤和移位青少年。采用分层区组随机1:1分配至Damon Q组(n = 35)或Victory组(n = 40),分配过程保密。在治疗前、治疗期间和治疗后,使用来自不同锥形束计算机断层扫描(CBCT)机器采集的CBCT图像,通过多平面重建对从切牙到磨牙的所有牙根进行EARR评估。

结果

62例患者纳入EARR分析。上颌切牙是受影响最严重的牙组,Damon组的平均EARR值为0.20mm,Victory组为0.51mm(无统计学差异,α = 1%)。该牙组中临床相关EARR的发生率,Damon组为5.0%,Victory组为7.2%(无统计学差异,α = 5%)。在中期影像学检查中仅发现1例治疗后有临床相关EARR的病例。

结论

两个治疗组中EARR的总体严重程度和发生率均低于临床相关水平。结果进一步证明,对于牙列拥挤的青少年非拔牙治疗,常规中期影像学检查对EARR的早期检测和预防似乎相关性有限。

试验注册

ClinicalTrials.gov:NCT05664282。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ebe/12056475/2531aa28f5f7/OCR-28-515-g001.jpg

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