Gaisa Michael, Deshmukh Ashish, Sigel Keith, Liu Yuxin
Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Department of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
Clin Infect Dis. 2025 Sep 16;81(2):345-347. doi: 10.1093/cid/ciaf052.
Recently published anal cancer screening guidelines recommend 5 strategies for high-risk populations using combinations of cytology and high-risk human papillomavirus testing. Based on data from 1223 persons with human immunodeficiency virus, all triage and cotesting strategies outperformed cytology alone. High-risk human papillomavirus testing improved specificity and reduced high-resolution anoscopy referrals, essential for guideline implementation.
最近发布的肛门癌筛查指南推荐了5种针对高危人群的筛查策略，这些策略结合了细胞学检查和高危型人乳头瘤病毒检测。基于1223例人类免疫缺陷病毒感染者的数据，所有分流和联合检测策略的效果均优于单独使用细胞学检查。高危型人乳头瘤病毒检测提高了特异性，并减少了高分辨率肛门镜检查的转诊率，这对于指南的实施至关重要。
