血小板淋巴细胞比率作为口腔癌患者的预后指标
Platelet Lymphocyte Ratio as a Prognosticator in Oral Cancer Patients.
作者信息
Hamad Bahiya Elrashid Khalid, Eltohami Yousif I, Suleiman Ahmed Mohamed
机构信息
Khartoum Teaching Dental Hospital, Khartoum, Sudan.
Faculty of Dentistry, University of Khartoum, Khartoum, Sudan.
出版信息
J Maxillofac Oral Surg. 2025 Feb;24(1):233-240. doi: 10.1007/s12663-023-01959-8. Epub 2023 Jul 12.
OBJECTIVE
To study the prognostic predictive value of the platelet lymphocyte ratio as a clinical parameter of the outcome of the Sudanese OSCC patients.
METHOD
Forty two oral cancer patients were selected for the study. The patients surgically managed in the period December 2018 to June 2020. The PLR was recorded and correlated with :the status of surgical margins, the lymphovascular invasion, the extranodal extension, the microscopic depth and the patient's survival (dead/ alive).
RESULT
A ratio of 170 was considered to be a cut off point of the PLR; as patients with a ratio higher than 170 were found to have a bad prognosis. Twenty-four patients (59.5%) had a PLR higher than 170. Patients with PLR equal to 170 or less have 45% decrease in the odds of survival and 57% decrease in the odds of having positive lymph nodes. Thirty-three percent passed away.
CONCLUSION
The PLR is an affordable, practical and efficient way to predict an OSCC patient's overall survival.
目的
研究血小板淋巴细胞比率作为苏丹口腔鳞状细胞癌患者预后临床参数的预测价值。
方法
选取42例口腔癌患者进行研究。这些患者于2018年12月至2020年6月期间接受手术治疗。记录血小板淋巴细胞比率，并将其与手术切缘状态、淋巴管浸润、结外扩展、显微镜下浸润深度以及患者生存情况（死亡/存活）进行关联分析。
结果
血小板淋巴细胞比率170被视为一个分界点；比率高于170的患者预后较差。24例患者（59.5%）的血小板淋巴细胞比率高于170。血小板淋巴细胞比率等于或低于170的患者生存几率降低45%，出现阳性淋巴结的几率降低57%。33%的患者死亡。
结论
血小板淋巴细胞比率是预测口腔鳞状细胞癌患者总体生存情况的一种经济、实用且有效的方法。
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