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袖状胃切除术中吻合器线的粘合与缝合对体重减轻的影响。

The Effect of Gluing Versus Suturing of the Stapler Line in Sleeve Gastrectomy on Weight Loss.

作者信息

Khalayleh Harbi, Hallaj Ashraf, Shweiki Amir, Bar-Zakai Barak, Sapojnikov Shimon, Imam Ashraf, Khalaileh Abed

机构信息

Department of Surgery, Kaplan Medical Center, Rehovot and the Hebrew University Medical School, Jerusalem, Israel.

The Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

出版信息

Obes Surg. 2025 Mar;35(3):895-901. doi: 10.1007/s11695-025-07728-5. Epub 2025 Feb 4.

DOI:10.1007/s11695-025-07728-5
PMID:39903412
Abstract

BACKGROUND

Stapler line reinforcement during sleeve gastrectomy (LSG) was assessed thoroughly in the context of postoperative complications focusing on leakage and bleeding. However, the effect of stapler line reinforcement techniques on the short- and long-term weight loss is still unclear and lacking. We hypothesize that inverting of the stapler line by Lembert suturing could lead to further additional reduction of the remnant gastric volume and accordingly a more significant weight reduction.

METHODS

Retrospective analysis of patients that underwent LSG (2012-2018) from the two university hospitals. The first hospital routinely performed oversewing with inversion of the stapler line (first group, Lembert suture), while the second university hospital performed LSG without stapler line oversewing and inversion, but routinely used VeraSeal glue (second group, non-Lembert); both groups were compared in terms of weight loss and complications.

RESULTS

Four hundred eighty and 550 patients underwent LSG in the first and second hospital, consequently. The mean BMI change and EBWL at 1, 3, and 5 years were better in the first group than in second group. The mean last follow-up BMI was significantly lower in Lembert group (29.8 ± 5.2kg/m) than in non-Lembert group (32.9 ± 6.7 kg/m), P = 0.001. The mean EBWL at last follow-up point was significantly better for the Lembert group as compared to non-Lembert group (73.7 ± 26.59 versus 57.12 ± 27.71, P = 0.001).

CONCLUSIONS

Lembert suture line oversewing and inversion in LSG is associated with noticeable improvement in weight loss outcomes at 1, 3, and 5 years and last follow-up compared to LSG with VeraSeal gluing.

摘要

背景

在袖状胃切除术(LSG)中,针对吻合器缝线加固的评估主要围绕术后并发症展开,重点关注渗漏和出血情况。然而,吻合器缝线加固技术对短期和长期体重减轻的影响仍不明确且缺乏相关研究。我们推测,采用伦伯特缝合法翻转吻合器缝线可进一步额外减小残余胃容积,从而实现更显著的体重减轻。

方法

对两家大学医院中接受LSG(2012 - 2018年)的患者进行回顾性分析。第一家医院常规采用翻转吻合器缝线的缝合方法(第一组,伦伯特缝合),而第二家大学医院进行的LSG未进行吻合器缝线缝合及翻转,但常规使用VeraSeal胶水(第二组,非伦伯特缝合);对两组患者的体重减轻情况和并发症进行比较。

结果

第一家医院和第二家医院分别有480例和550例患者接受了LSG。第一组在1年、3年和5年时的平均体重指数变化和额外体重减轻情况均优于第二组。伦伯特组的末次随访平均体重指数(29.8 ± 5.2kg/m²)显著低于非伦伯特组(32.9 ± 6.7 kg/m²),P = 0.001。与非伦伯特组相比,伦伯特组末次随访时的平均额外体重减轻情况明显更好(73.7 ± 26.59对57.12 ± 27.71,P = 0.001)。

结论

与使用VeraSeal胶水进行LSG相比,LSG中采用伦伯特缝合法进行缝线缝合及翻转与1年、3年、5年及末次随访时体重减轻效果的显著改善相关。

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本文引用的文献

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Obes Surg. 2023 Oct;33(10):3147-3154. doi: 10.1007/s11695-023-06781-2. Epub 2023 Aug 22.
2
Oversewing/Suturing of the Staple Line During Sleeve Gastrectomy Is an Effective and Affordable Staple Line Reinforcement Method: a Meta-analysis of Randomized Controlled Trials.胃袖状切除术时缝闭/缝合切割线是一种有效且经济的吻合口加固方法:一项随机对照试验的荟萃分析。
Obes Surg. 2023 Aug;33(8):2533-2545. doi: 10.1007/s11695-023-06672-6. Epub 2023 Jun 13.
3
Comparison of Laparoscopic Sleeve Gastrectomy Bleeding and Leakage Rates in Four Staple-Line Reinforcement Methods: A Prospective Observational Study.
四种缝钉线加固方法对腹腔镜袖状胃切除术出血和漏的比较:一项前瞻性观察研究。
J Laparoendosc Adv Surg Tech A. 2022 Nov;32(11):1176-1180. doi: 10.1089/lap.2022.0122. Epub 2022 Apr 25.
4
Early weight loss as a predictor of 3-year weight loss and weight regain in patients with good compliance after sleeve gastrectomy.术后良好依从性患者胃袖状切除术 3 年后的体重减轻和体重反弹的预测因子:早期体重减轻。
Surg Obes Relat Dis. 2021 Aug;17(8):1418-1423. doi: 10.1016/j.soard.2021.03.023. Epub 2021 Mar 28.
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Can staple-line reinforcement eliminate the major early postoperative complications after sleeve gastrectomy?胃袖状切除术的缝线加固能消除主要的早期术后并发症吗?
Asian J Surg. 2021 Jun;44(6):836-840. doi: 10.1016/j.asjsur.2020.12.036. Epub 2021 Jan 21.
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Impact of Resection Volume/Stapler Firings-Ratio on Perioperative Complications and Weight Loss After Laparoscopic Sleeve Gastrectomy.腹腔镜袖状胃切除术切除体积/吻合器击发次数比对围手术期并发症和减重效果的影响。
Obes Surg. 2021 Jan;31(1):207-214. doi: 10.1007/s11695-020-04870-0. Epub 2020 Jul 29.
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Residual Gastric Volume Relationship and Weight Loss After Laparoscopic Sleeve Gastrectomy.腹腔镜袖状胃切除术(LSG)后残胃容量与体重减轻的关系。
Obes Surg. 2020 May;30(5):1929-1934. doi: 10.1007/s11695-020-04417-3.
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Is There Necessity for Oversewing the Staple Line During Laparoscopic Sleeve Gastrectomy? An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.腹腔镜袖状胃切除术时是否有必要缝合吻合口?一项随机对照试验的更新系统评价和荟萃分析。
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