泛连接蛋白1六聚体起作用，但细胞更喜欢七聚体。
PANX1 hexamers work but cells prefer heptamers.
作者信息
Harris Andrew L
机构信息
Department of Pharmacology, Physiology, and Neuroscience, Rutgers New Jersey Medical School, Newark, NJ, USA.
出版信息
J Gen Physiol. 2025 Mar 3;157(2). doi: 10.1085/jgp.202413727. Epub 2025 Feb 5.
Abstract
Gupta et al. (https://doi.org/10.1085/jgp.202413676) reconcile a disconnect between structural and functional data regarding stoichiometry of PANX1 channels and provide new insights about channel activation.
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