Darnall Beth D, Abshire Lauren, Courtney Rena E, Davin Sara
Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, USA
Neurological Institute, Center for Spine Health, Cleveland Clinic, Cleveland, Ohio, USA.
Reg Anesth Pain Med. 2025 Feb 5;50(2):93-101. doi: 10.1136/rapm-2024-105601.
Perioperative skills-based interventions may support non-pharmacological management of pain and opioid reduction after surgery. Such interventions may target and enhance predictors for surgical recovery and possibly reduce chronic postsurgical pain. Existing meta-analyses are limited by inclusion of studies that are either non-surgical or with outcomes occurring only in the hours after surgery. Lacking is a scoping review of studies testing perioperative skills-based interventions for postsurgical pain relief and opioid reduction in the days and months after surgery. We reviewed the efficacy of perioperative behavioral interventions; over what time frame and in which surgical populations efficacy evidence exists; and whether such interventions can prevent chronic postsurgical pain. 20 randomized trials were included, with the following intervention types: hypnosis, relaxation therapy, stress management training, mindfulness, mixed-type skills interventions (mind-body skills, preoperative pain self-management, empowered relief for surgery); cognitive behavioral-therapy (CBT); and mindfulness-based CBT. We summarize study methods, treatment specifics, and analgesic effects. No studies were designed to test intervention efficacy for preventing chronic postsurgical pain. Only two studies used active controls as the study comparator. Two studies showed positive effects on postsurgical opioid use. No studies tested whether the interventions enhanced time to pain cessation after surgery. Four studies demonstrated durable analgesic effects at 3-12 months after surgery. We describe the real-world practicality of intervention integration into the perioperative pathway and provide dissemination and implementation methodologies that may increase intervention uptake and therefore fulfill calls from national agencies to better integrate behavioral pain treatments into perioperative care.
围手术期基于技能的干预措施可能有助于术后疼痛的非药物管理和减少阿片类药物的使用。此类干预措施可能针对并增强手术恢复的预测指标,并有可能减轻慢性术后疼痛。现有的荟萃分析受到纳入非手术研究或仅在术后数小时出现结果的研究的限制。缺乏对围手术期基于技能的干预措施在术后数天和数月缓解术后疼痛及减少阿片类药物使用的研究的范围综述。我们回顾了围手术期行为干预的疗效;存在疗效证据的时间框架和手术人群;以及此类干预措施是否可以预防慢性术后疼痛。纳入了20项随机试验,干预类型如下:催眠、放松疗法、压力管理训练、正念、混合型技能干预(身心技能、术前疼痛自我管理、手术赋能缓解);认知行为疗法(CBT);以及基于正念的CBT。我们总结了研究方法、治疗细节和镇痛效果。没有研究旨在测试干预措施预防慢性术后疼痛的疗效。只有两项研究使用积极对照作为研究比较对象。两项研究显示对术后阿片类药物使用有积极影响。没有研究测试干预措施是否能缩短术后疼痛停止的时间。四项研究表明在术后3至12个月有持久的镇痛效果。我们描述了将干预措施整合到围手术期路径中的实际可行性,并提供了可能会增加干预措施采用率的传播和实施方法,从而响应国家机构关于更好地将行为疼痛治疗整合到围手术期护理中的呼吁。