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音乐家肌张力障碍:关于新型预防和缓解治疗最有力证据的观点

Musician's dystonia: a perspective on the strongest evidence towards new prevention and mitigation treatments.

作者信息

Grifoni Joy, Crispiatico Valeria, Castagna Anna, Converti Rosa Maria, Ramella Marina, Quartarone Angelo, L'Abbate Teresa, Armonaite Karolina, Paulon Luca, Panuccio Francescaroberta, Tecchio Franca

机构信息

Faculty of Psychology and of Engineering, Uninettuno University, Rome, Italy.

Laboratory of Electrophysiology for Translational neuroScience LET'S, Institute of Cognitive Sciences and Technologies ISTC, Consiglio Nazionale delle Ricerche CNR, Roma, Italy.

出版信息

Front Netw Physiol. 2025 Jan 22;4:1508592. doi: 10.3389/fnetp.2024.1508592. eCollection 2024.

Abstract

This perspective article addresses the critical and up-to-date problem of task-specific musician's dystonia (MD) from both theoretical and practical perspectives. Theoretically, MD is explored as a result of impaired sensorimotor interplay across different brain circuits, supported by the most frequently cited scientific evidence-each referenced dozens of times in Scopus. Practically, MD is a significant issue as it occurs over 60 times more frequently in musicians compared to other professions, underscoring the influence of individual training as well as environmental, social, and emotional factors. To address these challenges, we propose a novel application of the FeeSyCy principle (feedback-synchrony-plasticity), which emphasizes the pivotal role of feedback in guiding inter-neuronal synchronization and plasticity-the foundation of learning and memory. This model integrates with established literature to form a comprehensive framework for understanding MD as an impaired FeeSyCy-mediated relationship between the individual and their environment, ultimately leading to trauma. The proposed approach provides significant advantages by enabling the development of innovative therapeutic and preventive strategies. Specifically, it lays the groundwork for multimodal psycho-physical therapies aimed at restoring balance in the neural circuits affected by MD. These strategies include personalized psychotherapy combined with physical rehabilitation to address both the psychological and physiological dimensions of MD. This integration offers a practical and value-added solution to this pressing problem, with potential for broad applicability across similar conditions.

摘要

这篇观点文章从理论和实践两个角度探讨了特定任务的音乐家肌张力障碍(MD)这一关键且最新的问题。从理论上讲,MD被认为是不同脑回路间感觉运动相互作用受损的结果,有最常被引用的科学证据支持——每一项在Scopus中都被引用了数十次。在实践中,MD是一个重大问题,因为与其他职业相比,它在音乐家中的发生率要高出60多倍,这突出了个体训练以及环境、社会和情感因素的影响。为应对这些挑战,我们提出了FeeSyCy原则(反馈-同步-可塑性)的一种新应用,该原则强调反馈在引导神经元间同步和可塑性(学习和记忆的基础)方面的关键作用。这个模型与现有文献相结合,形成了一个全面的框架,将MD理解为个体与其环境之间FeeSyCy介导的受损关系,最终导致创伤。所提出的方法通过开发创新的治疗和预防策略具有显著优势。具体而言,它为旨在恢复受MD影响的神经回路平衡的多模式心理-物理治疗奠定了基础。这些策略包括结合身体康复的个性化心理治疗,以解决MD的心理和生理层面问题。这种整合为这个紧迫问题提供了一个实用且增值的解决方案,具有在类似情况下广泛应用的潜力。

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