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使用专门设计的中空椎间融合器进行经皮椎弓根椎体内融合器强化联合短节段固定治疗晚期Kümmell病:与短节段固定椎体成形术比较的初步研究

Percutaneous Transpedicular Intravertebral Cage Augmentation with Short-Segment Fixation Using Specially Designed Cannulated Cage Trials for Advanced Kümmell Disease: A Preliminary Study Comparing with Vertebroplasty with Short-Segment Fixation.

作者信息

Park Sung Cheol, Cheh Gene, Kim Yongjung, Chung Hoon-Jae, Kang Min-Seok, Choi Ji-Hye

机构信息

Department of Orthopedic Surgery, Bumin Hospital Seoul, Seoul, Korea.

Department of Orthopedic Surgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.

出版信息

Clin Orthop Surg. 2025 Feb;17(1):29-38. doi: 10.4055/cios24276. Epub 2025 Jan 14.

Abstract

BACKGROUND

The treatment of Kümmell disease (KD) is controversial. Corpectomy and reconstruction or osteotomy with long-level fusion was traditionally performed for the advanced KD. However, these procedures can be disadvantageous for elderly patients. Several alternative surgical procedures including transpedicular intravertebral cage augmentation (TPICA) or vertebroplasty (VP) combined with short-segment fixation (SSF) have been suggested to minimize the surgical burden. This study aimed to compare the outcomes of percutaneous TPICA plus SSF with VP plus SSF for advanced thoracolumbar (T11-L2) KD and to introduce our novel percutaneous TPICA technique using specially designed cannulated cage trials.

METHODS

We devised specially designed cannulated cage trials to make the TPICA procedure safer and more reproducible, minimizing the risk of the pedicle medial wall violation. All consecutive patients who underwent percutaneous TPICA or VP combined with SSF for advanced thoracolumbar KD, from January 2021 to June 2022, with ≥ 1-year follow-up at a single institution, were included. Perioperative details, clinical outcomes (visual analog scale and Oswestry Disability Index), and radiological outcomes (anterior vertebral body compression percentage and vertebral kyphotic angle [VKA] of the fractured vertebra, and local Cobb angle [LCA]) were collected and compared between the groups.

RESULTS

A total of 42 patients were enrolled, with 21 patients in each group. There were no patients with pedicle medial wall fracture in the TPICA group. Both procedures provided significantly favorable radiological outcomes compared to those preoperatively. No significant differences were observed in the changes over time in all radiological parameters between the groups. Loss of correction during the follow-up period was significantly smaller in patients with TPICA than in those with VP in VKA (median [interquartile range], 2.15 [0.30-2.80] vs. 2.90 [0.90-6.53]; = 0.030) and LCA (2.70 ± 2.90 vs. 5.17 ± 4.40, = 0.037).

CONCLUSIONS

Both procedures are minimally invasive and useful options for advanced KD, especially for elderly patients with high comorbidity. Our novel percutaneous TPICA technique using cannulated cage trials, being safer and more reproducible, may allow spine surgeons to easily perform TPICA.

摘要

背景

Kümmell病(KD)的治疗存在争议。对于晚期KD,传统上采用椎体切除及重建或长节段融合截骨术。然而,这些手术对老年患者可能不利。有人提出了几种替代手术方法,包括经椎弓根椎体内植骨融合术(TPICA)或椎体成形术(VP)联合短节段内固定(SSF),以尽量减轻手术负担。本研究旨在比较经皮TPICA联合SSF与VP联合SSF治疗晚期胸腰段(T11-L2)KD的疗效,并介绍我们使用特殊设计的空心椎间融合器进行经皮TPICA的新技术。

方法

我们设计了特殊的空心椎间融合器,以使TPICA手术更安全、更可重复,将椎弓根内侧壁穿破的风险降至最低。纳入2021年1月至2022年6月在单一机构接受经皮TPICA或VP联合SSF治疗晚期胸腰段KD且随访≥1年的所有连续患者。收集并比较两组的围手术期详细情况、临床疗效(视觉模拟评分和Oswestry功能障碍指数)以及影像学疗效(骨折椎体的椎体前缘压缩百分比和椎体后凸角[VKA],以及局部Cobb角[LCA])。

结果

共纳入42例患者,每组21例。TPICA组无椎弓根内侧壁骨折患者。与术前相比,两种手术均取得了显著良好的影像学疗效。两组间所有影像学参数随时间的变化无显著差异。随访期间,TPICA组患者VKA(中位数[四分位间距],2.15[0.30 - 2.80]对2.90[0.90 - 6.53];P = 0.030)和LCA(2.70±2.90对5.17±4.40,P = 0.037)的矫正丢失明显小于VP组。

结论

两种手术都是治疗晚期KD的微创且有效的选择,尤其适用于合并症多的老年患者。我们使用空心椎间融合器的新型经皮TPICA技术更安全、更可重复,可能使脊柱外科医生更容易进行TPICA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca0/11791496/69465d613626/cios-17-29-g001.jpg

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