Elgayar Mohamed M, Negm Mahmoud A, Nasr Emad Gamaleldin, Abdullah Hedaia, Hamed Sayed, Honsy Hatem
Pediatric Intensive Care Unit, Aswan Heart Centre, Aswan, Egypt.
Department of Pediatrics, National Research Center, Cairo, Egypt.
World J Pediatr Congenit Heart Surg. 2025 Sep;16(5):661-667. doi: 10.1177/21501351241307950. Epub 2025 Feb 6.
IntroductionDiaphragmatic paralysis (DP) is a significant complication following cardiac surgery, particularly impacting neonates and infants. This retrospective study aims to evaluate the incidence of DP, identify risk factors, and assess the impact of diaphragmatic plication as a definitive management strategy.MethodsWe analyzed the clinical records of pediatric patients who underwent cardiac surgery at our center from 2016 to 2023. Cases of DP were identified, potential risk factors examined, and the effectiveness of plication assessed. Patients were categorized into early and late groups based on the timing of DP diagnosis relative to surgery.ResultsOut of 2,331 pediatric cardiac surgery patients (median age 7.2 months), DP was identified in 60 patients (2.6%), with a higher incidence of left-sided paralysis in 37 patients (61.7%). Diaphragmatic paralysis was more frequently associated with specific procedures, such as bidirectional Glenn, arterial switch operations, and Blalock-Taussig-Thomas shunt. Patients with DP had significantly longer intensive care unit (ICU) stays (21 vs 4 days, < .001) and total hospital stays (38 vs 11 days, < .001). Following plication, median mechanical ventilation (MV) hours significantly decreased (73-13 h, < .001), and ICU stays were reduced (15-3 days, < .001). Early plication was associated with shorter MV time and hospital stays.ConclusionDiaphragmatic paralysis is a notable complication after cardiac surgery. Diaphragmatic plication proves to be an effective intervention, reducing MV duration and hospital stays. These findings underscore the importance of early recognition and intervention for improved postoperative outcomes.
引言
膈神经麻痹(DP)是心脏手术后的一种重要并发症,对新生儿和婴儿影响尤为显著。本回顾性研究旨在评估DP的发生率,确定危险因素,并评估膈肌折叠术作为一种确定性治疗策略的效果。
方法
我们分析了2016年至2023年在本中心接受心脏手术的儿科患者的临床记录。确定DP病例,检查潜在危险因素,并评估折叠术的有效性。根据DP诊断相对于手术的时间将患者分为早期和晚期组。
结果
在2331例儿科心脏手术患者(中位年龄7.2个月)中,60例(2.6%)被诊断为DP,其中37例(61.7%)左侧麻痹发生率更高。膈神经麻痹与特定手术,如双向格林手术、动脉调转术和布莱洛克-陶西格-托马斯分流术更常相关。DP患者的重症监护病房(ICU)住院时间(21天对4天,<.001)和总住院时间(38天对11天,<.001)明显更长。折叠术后,机械通气(MV)中位小时数显著减少(73 - 13小时,<.001),ICU住院时间缩短(15 - 3天,<.001)。早期折叠术与较短的MV时间和住院时间相关。
结论
膈神经麻痹是心脏手术后的一种显著并发症。膈肌折叠术被证明是一种有效的干预措施,可减少MV持续时间和住院时间。这些发现强调了早期识别和干预对改善术后结果的重要性。