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[降钙素对胰岛素刺激的胃分泌的抑制作用。选择性评估胃分泌功能的一种可能性]

[Calcitonin inhibition of insulin-stimulated gastric secretion. A possibility of selective evaluation of gastric secretory function].

作者信息

Di Gesù G, Picone A B, Frazzetta M, Brancato L, Albano V, Averna M

出版信息

Arch Sci Med (Torino). 1979 Oct-Dec;136(4):531-6.

PMID:399172
Abstract

There is both clinical and experimental evidence for the antigastric effect of calcitonin. A study was therefore made of gastric secretion after maximum insulin stimulation, and during its inhibition by calcitonin. Evaluation of basal acid flow and the maximum acidity peak in these two tests showed that the difference between the two peaks was related to the increase in gastrin. This was not the case during inhibition. The results show that selective evaluation of gastric secretion enables selective surgical techniques to be employed in the treatment of duodenal ulcer.

摘要

降钙素具有抗胃作用,这既有临床证据,也有实验证据。因此,研究了最大胰岛素刺激后及降钙素抑制胰岛素刺激期间的胃分泌情况。对这两项测试中的基础酸排量和最大酸度峰值进行评估发现,两个峰值之间的差异与胃泌素的增加有关。在抑制期间情况并非如此。结果表明,对胃分泌进行选择性评估能够使选择性手术技术应用于十二指肠溃疡的治疗。

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