Knox Justin, Magana Christopher, Duncan Dustin T, Shrader Cho-Hee, Wilson Allison, Keedy Sarah, Pagkas-Bather Jade, Chen Yen-Tyng, Schneider John A
New York State Psychiatric Institute.
Department of Psychiatry, Columbia University Irving Medical Center.
AIDS. 2025 Jul 1;39(8):1032-1046. doi: 10.1097/QAD.0000000000004149. Epub 2025 Feb 7.
We conducted a systematic review evaluating the extant literature examining the impacts of cannabis use on HIV-related outcomes among Black sexual minoritized men (BSMM).
A systematic review.
We conducted a search in November 2024 of PubMed, EMBASE, CINAHL, PsycINFO, and Web of Science using keywords related to BSMM, HIV, and cannabis. Study quality was assessed utilizing a tool developed for observational studies. One hundred eight unique articles were screened with 55 undergoing full-text review, and 20 met inclusion criteria. Results were synthesized and presented utilizing a narrative review process.
We identified 20 studies published between 1999 and 2024. Measures of cannabis use included any use (e.g., ever, past 30 days), daily/intermittent/heavy use, use before/during sex, and problematic use. Outcomes included HIV positivity/seroconversion, HIV Continuum of Care (CoC), PrEP CoC, and sex behavior strengths, vulnerabilities, and assets. Study findings were generally mixed, however positive associations between cannabis use and HIV seroconversion, inconsistent condom use, being HIV-positive and unaware of one's serostatus, and suboptimal ART adherence were reported.
This systematic review identified a growing literature on cannabis use and HIV among Black SMM. Conclusions that can be drawn from the evidence are limited. There is a critical need for studies that more rigorously measure cannabis use by considering contexts of cannabis use. In addition, there is a need for research that examines the pathways and mechanisms through which cannabis use may affect prevention and treatments outcomes related to HIV among Black SMM.
我们进行了一项系统综述，评估现有文献，以研究大麻使用对黑人性少数群体男性（BSMM）与艾滋病毒相关结局的影响。
系统综述。
我们于2024年11月在PubMed、EMBASE、CINAHL、PsycINFO和科学网进行搜索，使用与BSMM、艾滋病毒和大麻相关的关键词。利用为观察性研究开发的工具评估研究质量。筛选了108篇独特的文章，其中55篇进行了全文审查，20篇符合纳入标准。结果采用叙述性综述流程进行综合和呈现。
我们确定了1999年至2024年发表的20项研究。大麻使用的衡量指标包括任何使用情况（例如，曾经使用、过去30天使用）、每日/间歇性/大量使用、性行为前/期间使用以及问题性使用。结局包括艾滋病毒阳性/血清转化、艾滋病毒连续护理（CoC）、暴露前预防连续护理（PrEP CoC）以及性行为的优势、脆弱性和资产。研究结果总体上参差不齐，但报告了大麻使用与艾滋病毒血清转化、不一致的避孕套使用、艾滋病毒呈阳性且未意识到自己的血清学状态以及抗逆转录病毒治疗依从性欠佳之间的正相关关系。
这项系统综述发现，关于黑人性少数群体男性中使用大麻与感染艾滋病毒的文献越来越多。从证据中得出的结论有限。迫切需要通过考虑大麻使用的背景来更严格地衡量大麻使用情况的研究。此外，还需要开展研究，以探讨大麻使用可能影响黑人性少数群体男性中与艾滋病毒相关的预防和治疗结局的途径和机制。
