Yamada Kouju, Kaneko Yoshiyuki, Konno Chisato, Furihata Ryuji, Otsuka Yuichiro, Kaneita Yoshitaka, Uchiyama Makoto, Suzuki Masahiro
Department of Psychiatry, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-ku, Tokyo, 173-8610, Japan.
Kumpukai Yamada Hospital, 3-4-10 Minamicho, Nishitokyo-shi, Tokyo, 188-0012, Japan.
Sci Rep. 2025 Feb 7;15(1):4582. doi: 10.1038/s41598-025-87897-6.
Insomnia symptoms and short sleep duration are known to be associated with suicidal ideation. The aim of this study was to investigate the association between nonrestorative sleep (NRS), a subjective experience of feeling unrefreshed after waking up, and suicidal ideation in the general population. We analyzed data from a cross-sectional survey of 2559 randomly sampled adults living in Japan. The participants were asked about insomnia symptoms (difficulty initiating sleep, difficulty maintaining sleep, and early morning awakening), NRS, sleep duration, and the presence of suicidal ideation. Logistic regression analysis was used to examine the associations among short sleep duration (< 6 h), insomnia symptoms, NRS, and suicidal ideation. Possible confounding factors were adjusted using propensity scores. In the multivariate analysis adjusting for the confounding effects of other sleep-related factors, in addition to psychiatric, sociodemographic, and lifestyle factors, only NRS showed a positive association with suicidal ideation (adjusted odds ratio [aOR] = 2.266). These findings suggest the importance of focusing on NRS for suicide prevention in the general population.
已知失眠症状和短睡眠时间与自杀意念有关。本研究的目的是调查非恢复性睡眠（NRS），即醒来后感觉没有恢复精力的主观体验，与普通人群自杀意念之间的关联。我们分析了对居住在日本的2559名随机抽样成年人进行的横断面调查数据。参与者被问及失眠症状（入睡困难、维持睡眠困难和早醒）、NRS、睡眠时间以及自杀意念的存在情况。采用逻辑回归分析来检验短睡眠时间（<6小时）、失眠症状、NRS和自杀意念之间的关联。使用倾向得分对可能的混杂因素进行调整。在多变量分析中，除了对精神、社会人口统计学和生活方式因素进行调整外，还对其他与睡眠相关因素的混杂效应进行了调整，结果显示只有NRS与自杀意念呈正相关（调整后的优势比[aOR]=2.266）。这些发现表明，在普通人群中预防自杀时关注NRS具有重要意义。
