Liu Yi, Jia Congwei, Wang Zhan, Zhang Yushi
Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Endocrine. 2025 May;88(2):431-433. doi: 10.1007/s12020-025-04174-2. Epub 2025 Feb 7.
Bladder Paraganglioma (BPG) is a rare form of pheochromocytoma and paraganglioma (PPGL) characterized by elevated blood pressure when urinating, headache, dizziness, palpitations, and hematuria. Surgical resection is the most commonly used treatment for BPG. Here, we reporte a man who initially presented with hypogastralgia and hematuria and was diagnosed as BPG at local hospital. The size of mass was too huge to receive partial cystectomy at diagnosis. Then this patient was referred to our medical center. After evaluation, we chose temozolomide as neoadjuvant therapy to reduce the tumor size. Followed by seven cycles of temozolomide, the tumor was decreased and was successfully removed via partial cystectomy.
膀胱副神经节瘤（BPG）是嗜铬细胞瘤和副神经节瘤（PPGL）的一种罕见形式，其特征为排尿时血压升高、头痛、头晕、心悸和血尿。手术切除是BPG最常用的治疗方法。在此，我们报告一名男性患者，最初表现为下腹痛和血尿，在当地医院被诊断为BPG。诊断时肿块太大，无法进行部分膀胱切除术。然后该患者被转诊至我们的医疗中心。经过评估，我们选择替莫唑胺作为新辅助治疗以缩小肿瘤大小。在进行七个周期的替莫唑胺治疗后，肿瘤缩小，通过部分膀胱切除术成功切除。
